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Company insight The defence of antibiotics


With the fight against antibiotic resistance increasing, so is the importance of a more sensitive and faster diagnosis to offer a personalised treatment. CerTest has responded to that by developing a range of multiplex reactions for the detection and differentiation of multiple genes, which confer resistance to antibiotics – chiefly, through its Viasure products.


esistance to antimicrobials is now a serious public health problem, being one of the biggest threats to health on a global scale. The discovery and introduction of antimicrobials in clinical practice was one of the greatest advancements in medicine, and this period is known as the ‘antibiotic age’. However, excessive use has resulted in such microorganisms losing their natural sensitivity to these agents over time through the selection and transmission of various resistance mechanisms. This loss of antibiotic sensitivity was resolved by the development of new antimicrobials. However, the emergence of multiresistant bacteria and the poor prospects for developing new antimicrobials over the


R


next decade indicate that this model cannot be maintained and could lead to an antibiotic crisis.


Crisis of efficiency


The current problem of antimicrobial resistance, together with the delay in conventional diagnostic methodologies, makes it difficult for clinicians to choose the optimal treatment to administer to the patient, thus worsening the situation of the patient. This is why alternative techniques to conventional diagnosis are required that present greater speed, sensitivity, specificity and ability to detect microorganisms, along with their antibiotic resistance mechanism. In addition, techniques are sought with the highest degree of automation possible, ease


of implementation and a good cost- effectiveness ratio.


As a solution to this problem,


CerTest Biotec has developed different multiplex reactions for the detection and differentiation of multiple genes that confer resistance to antibiotics, along with the identification of the most prevalent bacteria to present such resistance mechanisms in a short period of time, from sample processing to automatic interpretation of results. These Viasure products can be used in combination or individually, in such a way to allow designing different combinations according to the needs of the laboratory. ●


www.certest.es/viasure


Practical Patient Care / www.practical-patient-care.com


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