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PPi Editor Andy Myall andymyall@stepcomms.com


Science Editor Brian Nation CSci FIBMS briannation@stepcomms.com


Publisher Geoff King geoffking@stepcomms.com


Business Manager Peter Moon


petermoon@stepcomms.com


Journal Administration Katy Cockle katycockle@stepcomms.com


Design Laurence Hallam


Publishing Director Trevor Moon trevormoon@stepcomms.com


Advisory Panel Dr Nigel Brown FIBMS Gavin Knight CSci FIBMS Wendy Leversuch CSci FIBMS Dr Suzy Lishman CBE FRCPath Dr Stephen MacDonald FRCPath Prof Gerry McKenna DSc CSci FIBMS Malcolm Needs CSci FIBMS Dr Sarah Pitt CSci FIBMS Dr John Rees FIBMS


Pathology in Practice may not be reproduced in any way without prior written consent of the publisher.


Step House, North Farm Road Tunbridge Wells Kent TN2 3DR Tel: 01892 779999


Email: info@pathologyinpractice.com ISSN 1465-9131


Register your details to receive free copies of the magazine. SCAN HERE


Escherichia coli in human health and disease, see page 22


CONTENTS


Volume 26 Issue 1 February 2025


www.pathologyinpractice.com OPINION


The Innovation Ecosystem Programme: life-sciences powered growth for the UK


NEWS ARTICLES


Celebrating 40 years of BSMT microbiology conferences: a milestone meeting


The SHOT Report 2023: Can opportunity follow learning from adversity?


Escherichia coli: an exploration of its role in human health and disease


Introduction to risk management frameworks in clinical laboratories


From HeLa to CellNass; the development of tissue archiving


The development of tissue archiving, see page 33


Antimicrobial stewardship and diagnostics needed to tackle the threat of AMR


Joined-up IT systems – Clinisys ICE Summit shows the way forward


Harnessing AI for digital pathology in clinical and diagnostic workflows


Digital pathology: ensuring a return on investment


Harnessing AI for digital pathology, see page 45


Platelets and platelet counting: a selection of recent topics of investigation


The rise of the latex particles! 14 17 22 29 33 38 41 45 51 55 COVER STORY


The ever-changing world of laboratory diagnostics surrounds us with innovation for speed, accuracy, convenience, and reduced turnaround time in the patient clinical care pathway. Spare a thought for the convenience, speed, and reliability of the latex particle. Prolex rapid latex agglutination systems offer fast, clear, and sensitive results for the identification of streptococci, staphylococci, Legionella, Escherichia coli O157, and non-O157, due to a unique manufacturing process to enhance performance using carboxylate-modified microparticles (CM-MP) and chemical cross-linking agents. Numerous approaches have been developed for covalent attachment of biological molecules to microparticles, but CM-MP represents a significant improvement over the traditional latex kits in terms of product performance characteristics, giving faster, clearer and more specific reactions. All kits are presented in user- and environment-friendly modular packaging with


recyclable cardboard. T: 0151 353 1613 E: uksupport@pro-lab.co.uk W: www.pro-lab.co.uk


WWW.PATHOLOGYINPRACTICE.COM FEBRUARY 2025 3


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PATHOLOGY IN PRACTICE


PPi


www.pathologyinpractice.com VOLUME 26 • ISSUE 1 • FEBRUARY 2025


INTRODUCTION TO RISK MANAGEMENT FRAMEWORKS IN CLINICAL LABORATORIES


40 YEARS OF BSMT MICROBIOLOGY CONFERENCES: A MILESTONE MEETING


ESCHERICHIA COLI: AN EXPLORATION OF ITS ROLE IN HUMAN HEALTH AND DISEASE


THE RISE OF THE LATEX PARTICLES!


PATHOLOGY IN PRACTICE


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