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for many years. The US Food and Drug Administration has


recommended that it is not necessary for skin antiseptics to be manufactured as sterile products, but they should be packaged in single-use containers and appropriately labelled by manufacturers to reduce the risk of in use contamination.3


Following customer feedback,


Ecolab has also evolved Videne Antiseptic Solution from a multi-use to a single-use medicinal application.


With the above developments, Ecolab can


now offer three single use pre-operative skin preparation solutions to customers, both chlorhexidine and povidone iodine based: 1. Prevase, for preoperative skin disinfection prior to surgical procedures.


2. Prevase Stain, for preoperative skin disinfection prior to surgical procedures.


3. Videne Antiseptic Solution: a. For once-only use: Disinfection of intact external skin or as a mucosal antiseptic, for example prior to surgery, biopsies, injections, punctures, blood-taking and bladder catheterisations. b. For repeated, time-limited use: Antiseptic wound treatment (e.g., decubitus and varicose ulcers), burns, infected and superinfected dermatoses.


A sustainable solution for Theatres As described in the Intercollegiate Green Theatre Checklist from the Royal College of Surgeons, globally healthcare facilities have a significant carbon footprint, accounting for 4-5% of total carbon emissions. Surgery is particularly carbon intensive, with a typical single operation estimated


Essential information


Name: Prevase Chlorhexidine Gluconate 0.5% w/v in 70% v/v DEB Cutaneous Solution. Active Ingredient: Chlorhexidine Gluconate Solution 20% BP (Ph Eur) 2.5% v/v Indication: For pre-operative skin disinfection prior to surgical procedures MAH: Ecolab Ltd, Unit 1, Wernddu Court, Caerphilly CF83 3SG, UK


Legal Status: GSL Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at: https://products.mhra.gov.uk/ search/?search=prevase&page=1


Name: Prevase Stain Chlorhexidine Gluconate 0.5% w/v in 70% v/v DEB Cutaneous Solution. Active Ingredient: Chlorhexidine Gluconate Solution 20% BP (Ph Eur) 2.5% v/v Indication: For pre-operative skin disinfection prior to surgical procedures MAH: Ecolab Ltd, Unit 1, Wernddu Court, Caerphilly CF83 3SG, UK


Legal Status: GSL Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at: https://products.mhra.gov.uk/ search/?search=prevase+stain&page=1


Name: Videne Antiseptic Solution 10% w/w Cutaneous Solution Active Ingredient: 10% povidone-iodine w/w Indication: For once-only use: Disinfection of intact external skin or as a mucosal antiseptic, for example prior to surgery, biopsies, injections, punctures, blood-taking and bladder catheterisations. For repeated, time-limited use: Antiseptic wound treatment (eg, decubitus and varicose ulcers), burns, infected and superinfected dermatoses. MAH: Ecolab Ltd, Unit 1, Wernddu Court, Caerphilly CF83 3SG, UK


Legal Status: P Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at: https://products.mhra.gov.uk/search/? search=videne+antiseptic+solution&page=1


Name: Videne Alcoholic Tincture Active Ingredient: 10% povidone-iodine w/w Indication: For quick drying pre-operative skin disinfection, particularly in orthopaedic surgery. MAH: Ecolab Ltd, Unit 1, Wernddu Court, Caerphilly CF83 3SG, UK Legal Status: P Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at: https://products.mhra.gov.uk/ search/?search=videne+alcoholic+tincture&page=1


Name: Hydrex Surgical Scrub Chlorhexidine 4% w/v Skin Cleanser. Active Ingredient: Chlorhexidine Gluconate 4% w/v Indication: For use as an antiseptic hand wash, a pre-operative hand scrub and a pre-operative skin preparation to surgery. MAH: Ecolab Ltd, Unit 1, Wernddu Court, Caerphilly CF83 3SG, UK Legal Status: GSL Information about this product, including adverse reactions, precautions, contra-indications, and method of use can be found at: https://products.mhra.gov.uk/ search/?search=hydrex+surgical+scrub&page=1


May 2024 I www.clinicalservicesjournal.com 7


A national team of clinical experts to support operating theatres throughout the UK Ecolab understands the importance of clinical expertise to provide training and education to customers. A national team of clinically trained specialists from Ecolab support the implementation of infection prevention solutions with expert counsel to help identify improvement opportunities across the hospital. Ecolab also have a dedicated clinical skin


specialist within the UK team, Sarah Brown. Prior to joining Ecolab, Sarah has 30 years’ experience working as a theatre scrub nurse in the NHS alongside a diploma in Infection Prevention & Control and Surgical Site Infection qualification certified by the WHO. “I am so passionate about increasing patient safety whilst reducing the risk of SSI’s. For me it is not just about selling a product, I love being able to support and educate on best practice with our products. I am proud to be part of a national team of clinical specialists, who like me, all have experience of working in theatres and can support the hospitals throughout the UK. We have been supplying pre-operative skin antisepsis products for many years and are the only supplier


References 1. Surgical site infections: prevention and treatment. NICE guideline [NG125]. Antiseptic Skin Preparation. Recommendations | Surgical site infections: prevention and treatment | Guidance | NICE


2. Wilson, Professor J. White Paper. Evidence for 0.5% Chlorhexidine in 70% alcohol as a preoperative skin antiseptic for the prevention of surgical site infection. 2024.


3. FDA drug safety communication: FDA requests label changes and single-use packaging for some over-the-counter topical antiseptic products to decrease risk of infection. Clin Infect Dis. 2014 Feb;58(3):i-ii. PMID: 24571007


4. Royal College of Surgeons. Intercollegiate Green Theatre Checklist.


to generate between 150-170 kgCO2e, equivalent to driving 450 miles in an average petrol car.4 Ecolab pre-operative skin preparation products


are supplied in recyclable bottles, designed to be poured into gallipots and applied using sponge- holders and swabs. This method is also referenced in the Intercollegiate Green Theatre Checklist, stating that the NICE guidance suggests that pouring antiseptic solutions into reusable gallipots and applying them using reusable instruments and swabs have a reduced environmental impact.4


in the UK who can offer a product against every level of the NICE NG125 Guidelines for Antiseptic Skin Preparation.” Sarah Brown, Clinical & Skin Specialist, Ecolab Healthcare UK.


Want to learn more? Come and see us! To learn more about Ecolab’s solutions and how our team can support you, please reach out to arrange a visit to our customer innovation centre at our UK head office using my details below.


Isabelle West,


Marketing Lead UK, IE & Nordics Isabelle.west@ecolab.com


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