Cover story - advertising feature


A complete solution for pre-operative skin antisepsis


Ecolab, a global sustainability leader in water and hygiene, is reinforcing its commitment to protecting people and vital resources with updates to its Healthcare portfolio.


As the only supplier offering a full range of pre-operative skin preparation in the UK, Ecolab is providing comprehensive solutions for all perioperative procedures. Ecolab is also introducing updates to its Prevase


and Prevase Stain products, that have received an enhanced indication “for preoperative skin disinfection prior to surgical procedures”. In our continuous effort to innovate and address our customers’ challenges, we continue to provide sustainable packaging solutions that aim at reducing carbon emissions in operating theatres. For over 30 years, we have been supplying


medicinal products to operating theatres, and these new developments underscore our dedication to innovation and sustainability, helping to shape the future of healthcare.


Infection prevention solutions for the operating theatre Ecolab is a major supplier of key products that are used in every hospital and operating theatre across


When1 First choice unless


contraindicated or the surgical site is next to a mucous membrane


Alternative if the surgical site is next to a mucous


membrane Alternative if chlorhexidine


is contraindicated


If both an alcohol-based solution and chlorhexidine are unsuitable


Figure 1: Ecolab Solutions 6 www.clinicalservicesjournal.com I May 2024


Choice of antiseptic skin preparation1


Alcohol-based solution of


chlorhexidine


the country, working in partnership with customers to improve outcomes and operational efficiencies. From hand scrubbing prior to a surgical procedure, to the preoperative skin preparation portfolio, Ecolab plays a critical infection prevention role in the perioperative environment, supplying licenced medicinal products for these applications. Ecolab is also sole supplier of povidone-iodine


based preoperative skin antiseptics in the UK and Ireland. Clinicians and patients require a range of preoperative skin preparation products for a wide variety of clinical applications. Ecolab is the only supplier in the UK to have a complete solution for pre-operative skin preparation, in line with the NICE guideline NG125 Surgical site infections: prevention and treatment1


shown in figure 1 (below).


Evidence for 0.5% Chlorhexidine in 70% Alcohol as a preoperative skin antiseptic A recent review of the evidence for 0.5% chlorhexidine (CHG) in 70% alcohol as a


Ecolab Solution


Prevase Chlorhexidine Gluconate 0.5% w/v in 70% v/v DEB Cutaneous Solution and


Prevase Stain Chlorhexidine Gluconate 0.5% w/v in 70% v/v DEB


Cutaneous Solution


Aqueous solution of chlorhexidine


Alcohol-based


solution of povidone-iodine Aqueous solution of


povidone-iodine


Hydrex Surgical Scrub Chlorhexidine 4% w/v Skin Cleanser


Videne Alcoholic Tincture Povidone-iodine w/w


Videne Antiseptic Solution 10% w/w Cutaneous Solution


Thanks to the evidence review, Ecolab has recently had updates to the existing pre-operative skin antisepsis portfolio. Prevase (PL 04509/0062) and Prevase Stain (PL 04509/0063) are both a single use 0.5% Chlorhexidine Gluconate w/v in 70% denatured ethanol v/v solution which have historically held a therapeutic indication for preoperative skin disinfection prior to minor surgical procedures. This therapeutic indication has since been updated to state “for preoperative skin disinfection prior to surgical procedures”. This therefore means that the Prevase and


Prevase Stain indication is no longer limited to minor surgery and now includes major surgeries as well. The updated Summary of Product


Characteristics are available from the MHRA using the following link: https://products.mhra.gov.uk/ search/?search=prevase&page=1


Innovating to meet our customers’ needs: single use product development Videne Antiseptic Solution is a medicinal product authorised by the MHRA and has been widely used


www.clinicalservicesjournal.com Volume 23 I Issue 5 I May 2024


THE CLINICAL SERVICES JOURNAL


Preventing SSIs:


the butterfly effect Controversies surrounding PA and AA roles HealthTech: a lever for delivering new paradigms


pre-operative skin antiseptic by Professor Jennie Wilson, concluded2


:


l CHG is highly bactericidal at concentrations of 0.02%.


l 0.5% CHG suppresses microbial growth on skin for at least 72hrs after application.


l There is no evidence that 0.5% CHG/70% alcohol is less effective than 2% CHG in preventing surgical site infections (SSI).


l NICE and other clinical guidelines on prevention of SSI do not recommend using 2% CHG in preference to 0.5% CHG to prevent SSI.


l Higher concentrations of chlorhexidine may increase the risk of skin irritation and allergic reaction.


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