INF ECT ION PR EVENT ION & CONT ROL
Discussion
As resistance to both disinfectants and antibiotics is on the increase, and as the inter relationship between the two resistance profiles are inexorably linked, we have to think of a new way to deal with these issues individually and together. There can be no doubt that the choice of disinfecting chemistry should now be in the minds of everyone involved in control of infections
in our hospitals (there is a case for saying that it is important for everyone entering a hospital, including patients and visitors). The results shown in this article, and the ever-increasing volume of evidence proving the links between antibiotic and disinfectant resistance, would suggest that it is possible to select the ideal properties for both the skin and surface disinfectant of choice. These properties would be:
2000 1900 1800 1700 1600 1500 1400 1300 1200 1100 1000 900 800 700 600 500 400 300 200 100 0
2,003 1,893 1,682 1,704 1,6881,684 1,564 1,722 1,779 1,718 1,732
2% CHG in 70% Alcohol 0.5% CHG in 70% Alcohol 7.5% Pl in 70% Alcohol 70% Alcohol
5th Generation Si Quat
l Full spectrum of species kill. l Fast acting. l Long lasting. l Not prone to acquired or innate resistance. l Safe to use. l Simple to use. l Safe for the environment. l Inexpensive to use.
From the choices available today, there is only one surface and skin disinfectant that possesses all eight of the properties listed above and that is the 5th generation SiQuats. Therefore, by mixing multiple chemistries, none of which individually possess all of the above, but together do, it is reasonable to assume that the theory of “Holism” applies in the case of 5th generation SiQuats.
863 759 621 171 183 59 Pre Treatment 48 5 mins post 206 154 143 15 1 hour post 148 13 2 hours past 11 4 hours past Figure 3b: Comparison of average CFU counts: skin surgical prep after cationic soap
50000 45000 40000 35000 30000 25000 20000 15000 10000 5000 0
47,085
5th Generation Si Quat 5 mins post application Application once every 30 days (After 3 months) Application once every 30 days (After 6 months) 48,170
37,200
It crucial to note that our formulation of 5th generation SiQuats is microbiocidal for all the micro-organisms cited by the US CDC as being responsible for most hospital- acquired infections. The most frequent and virulent microorganisms causing hospital acquired infections include methicillin- resistant Staphylococcus aureus (MRSA), Acinetobacter baumannii, carbapenem resistant Enterobacteriaceae (CRE), especially Klebsiella pneumoniae and Escherichia coli, and Clostridioides difficile (C. difficile). Candida auris is causing a new and deadly fungal infection that it is spreading across the United States. The only types of skin and surface disinfectants currently available that are proven to kill all of these microbes are the 5th generation SiQuats.
16,830 19,467 21,838 321 103 15 Patient check-in screen 76 20 15 Entry touch pad 42 9 90
Treatment room door handle
251 18 32
Computer keyboard
165 49 245
Waiting room chair
Figure 4: Implementation of a 5th generation Si Quat in a GP clinic Pre-treatment
4000 3500 3000 2500 2000 1500 1000 500 0
5th Generation SiQuat 2785 97 32 159
Check-in desktop
There are two final points to make, without proper guidance on both type and frequency of surface and skin testing, it is difficult to see how healthcare systems around the world will reduce infection rates. It would also seem pointless to spend enormous amounts of money on the development of new antibiotics, to see resistance to them emanating at least in part from the poor choice and/ or use of surface and skin disinfectants.
About the author 418 3 Treatment Before
Treatment with Q shield
After 0 Treatment Treatment Treatment
14 days after
28 days after
Wooden chopping board Figure 5: Food chopping board results 24 l
WWW.CLINICALSERVICESJOURNAL.COM OCTOBER 2020
7 days after
3 0 Treatment Before 0
Treatment with Q shield
After 0 Treatment Treatment Treatment
14 days after
28 days after
Plastic chopping board
7 days after
0 1
Dr Andrew Kemp JP PhD is the head of the Scientific Advisory Board, British Institute of Cleaning Science; UK ambassador, Anti Microbial Resistance Insights; principal scientific advisor to: CP Medical, Gateway Health, Axenic Health, Pierce Innovations and the Q Technologies Group; and the infection control officer for: Wimpole Aesthetic Clinic London and Zenith clinics, Nottingham.
CSJ
Average bacterial CFU counts per cm2
Average bacterial CFU counts per cm2 Average bacterial CFU counts per cm2
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