INFECTION DIAGNOSTICS :: STIs
ficient, and effective sexual health care that includes testing with a superior sample type — the vaginal swab.
REFERENCES
1. Schachter J, Chernesky MA, Willis DE, Fine PM, Martin DH, Fuller D, et al. Vaginal swabs are the specimens of choice when screening for Chlamydia trachomatis and Neisseria gonor- rhoeae: results from a multicenter evaluation of the APTIMA assays for both infections. Sex Transm Dis. 2005 Dec;32(12):725-8.
2. Chernesky MA, Jang D, Gilchrist J, Hatchette T, Poirier A, Flandin J-F, et al. Head-to-head comparison of second-generation nucleic acid amplification tests for detection of Chlamydia trachomatis and Neisseria gonorrhoeae on urine samples from female subjects and self- collected vaginal swabs. J Clin Microbiol. 2014;52(7):2305-2310.
3. Van Der Pol, B, Williams JA, Fuller D, Taylor SN, Hook EW. Combined testing for Chlamydia, Gonorrhea, and Trichomonas by use of the BD Max CT/GC/TV Assay with genitourinary speci- men types. J Clin Microbiol. 2016;55(1):155-164.
4. Van Der Pol B, Fife K, Taylor SN, Nye MB, Chavoustie SE, Eisenberg DL, et al. Evaluation of the performance of the Cobas CT/NG test for use on the Cobas 6800/8800 systems for detection of Chlamydia trachomatis and Neisseria gonor- rhoeae in male and female urogenital samples. J Clin Microbiol. 2019;57(4):e01996-18.
5. Coorevits L, Traen A, Bingé L, Van Dorpe J, Praet M, Boelens J, et al.: Identifying a consensus sample type to test for Chlamydia trachomatis, Neisseria gonorrhoeae, Myco- plasma genitalium, Trichomonas vaginalis and human papillomavirus. Clin Microbiol Infect. 2018;24(12):1328-1332.
6. Falk L, Coble B-I, Mjörnberg, Fredlund H. Sampling for Chlamydia trachomatis infec- tion – a comparison of vaginal, first-catch urine, combined vaginal and first-catch urine and endocervical sampling. Int J STD AIDS. 2010;21(4):283-287.
7. Hobbs MM, van der Pol B, Totten P, Gaydos CA, Wald A, Warren Tet al. From the NIH: pro- ceedings of a workshop on the importance of self-obtained vaginal specimens for detection of sexually transmitted infections. Sex Transm Dis. 2008;35(1):8-13.
8. Michel C-E C, Sonnex C, Carne CA, White JA, Magbanua JPV, Nadala Jr ECB, et al. Chlamydia trachomatis load at matched anatomic sites: implications for screening strategies. J Clin Microbiol. 2007;45(5):1395-1402.
9. Chernesky MA, Hook EW, Martin DH, Lane J, Johnson R, Jordan JA, et al. Women find it easy and prefer to collect their own vaginal swabs to diagnose Chlamydia trachomatis or Neisseria gonorrhoeae infections. Sex Transm Dis. 2005;32(12):729-733.
10. Fielder RL, Carey KB, Carey MP. Acceptabil- ity of STI testing using self-collected vaginal
swabs among college women. J Am Coll Health. 2013;61(1):46-53.
11. Centers for Disease Control and Prevention. Recommendations for the laboratory-based detection of Chlamydia trachomatis and Neis- seria gonorrhoeae—2014. MMWR Recomm Rep. 2014 Mar 14;63(RR-02):1-19.
12. Blake DR, Maldeis N, Barnes MR, Hardick A, Quinn TC, Gaydos CA. Cost-effectiveness of screening strategies for Chlamydia trachomatis using cervical swabs, urine, and self-obtained vaginal swabs in a sexually transmitted disease clinic setting. Sex Transm Dis. 2008;35(7):649-655.
13. Gettinger J, Van Wagoner N, Daniels B, Boutwell A, Van Der Pol B. Patients Are Willing to Wait for Rapid Sexually Transmitted Infection Results in a University Student Health Clinic. Sexual Transm Dis. 2019;47(1):67-69.
14.Workowski KA, Bachman LH, Chan PA, John- ston CM, Muzny CA, Park I, et al. Sexually trans- mitted infections treatment guidelines, 2021. MMWR Recomm Rep. 2021 Jul 23;70(4):1-187.
15. Martin DH. Mycoplasma genitalium infection in men and women. UpToDate. April 2, 2021. Accessed July 27, 2021.
16. Getman D, Jiang A, O’Donnell M, Cohen S. Mycoplasma genitalium prevalence, coinfection, and macrolide antibiotic resistance frequency in a multicenter clinical study cohort in the United States. J Clin Microbiol. 2016;54(9):2278-2283.
17. Gaydos C, Maldeis NE, Hardick A, Hardick J, Quinn TC. Mycoplasma genitalium as a con- tributor to the multiple etiologies of cervicitis in women attending sexually transmitted disease clinics. Sex Transm Dis. 2009;36(10):598-606.
18. Gaydos CA, Manhart LE, Taylor SN, et al. Molecular testing for Mycoplasma genitalium in the United States: Results from the AMES Prospective Multicenter Clinical Study. J Clin. Microbiol. 2019;57(11): e01125-19.
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19. Manhart LA, Gaydos CA, Taylor SN, et al. Characteristics of Mycoplasma genitalium uro- genital infection in a diverse patient sample from the United States: results from the Aptima Myco- plasma genitalium Evaluation Study (AMES). J Clin Microbiol. 2020;58:e00165-20.
20. Trent M, Yusuf HE, Perin J, Anders J, Chung SE, Tabacco-Saeed L, Rowell J, Huettner S, Rothman R, Butz A, Gaydos CA. Clearance of Mycoplasma genitalium and Trichomonas vagi- nalis among adolescents and young adults with pelvic inflammatory disease: results from the Tech-N study. Sexually transmitted diseases. 2020 Nov 1;47(11):e47-50.
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PROVEN DIAGNOSTIC PERFORMANCE
Barbara Van Der Pol is a Professor of Medicine and Public Health at the University of Alabama at Birmingham and the Director of the UAB STD Diagnostics Laboratory. Her research focuses on understanding the
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biological and behavioral factors that affect susceptibility to, and prevention of sexually transmitted infections (STIs), and she is active on projects designed to improve access to sexual health for underserved and minority populations. She currently serves as the President of the International Society for STD Research.
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