CHROMATOGRAPHY


Torrey Pines Scientifi c’s new EchoTherm Model CO50 HPLC column chiller/heater


fl ow path allows for alternate carrier gas use and safely vents vials. Also, because the complete HS-GC system is on the GC touchscreen, customers can easily communicate with it anywhere the lab network will allow.


IN THE WATERS Meanwhile, Waters has just launched a new MAM workfl ow for the BioAccord LC-MS system. T e new workfl ow will enable drug development, manufacturing and QC scientists to monitor effi cacy and safety through the analysis of critical quality attributes (CQAs) of monoclonal antibodies (mAbs) and other protein- based drugs. “T e BioAccord System moves attribute-based monitoring out of centralised MS labs and into the hands of more scientists in regulated and quality control laboratories who may not have extensive experience operating mass spectrometers,” says Jeff Mazzeo from Waters. “With this new method for the BioAccord System on the waters_connect platform, scientists have a single, sensitive multiplexed method to accurately assess the most important attributes of protein- based drugs that enable rapid decision- making for product development, manufacturing and release.”


LATEST MODEL In another new development, US- headquartered Torrey Pines Scientifi c has launched its new EchoT erm Model CO50 Programmable HPLC column chiller/heater.


T e unit has a temperature range from 4.0°C to 100.0°C readable and settable to 0.1°C. T e PID control software regulates temperatures to ±0.2°C, even at ambient. T e CO50 has a stable temperature LED that illuminates when the target temperature is stable to within ±0.2°C. T e Peltier-based CO50 has fi ve-


program memory of 10 steps per program and the ability to repeat any program from 1 to 99 times automatically. It is ideal for chiral and biomedical chromatography where below ambient temperatures help preserve bioactivity. It can be used for stabilising column temperatures from day to day at or near room temperatures for repeatable results. T e CO50 holds columns up to 30cm long by ¼in or 3/8in diameter in mounting clips provided. Larger diameter columns can be used by removing the column clips that hold the smaller columns. It features RS232 I/O port


for controlling the unit by a chromatograph, for programming gradients, and for data collection. Also included are an injection counter, 30-day timer with user settable Auto-Off and chamber drain for spills.


ADVANCED SOLUTIONS In liquid chromatographs news, Shimadzu has launched its Advanced i-Series products. T e Prominence-i HPLC and Nexera-i UHPLC systems feature pressures of 50MPa or 70MPa respectively


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and can be combined with a variety of detectors. T e Advanced i-Series meets user demands for analysing a large number of samples or quickly re-processing data even when working from home. Retaining the basic functions of the compact i-Series instruments, the Advanced i-Series boasts increased pressure resistance and additional functions to support remote work. Both the system itself and the dedicated software enable reliable data acquisition for all users, with automation to replicate the handling of expert operators. T e Advanced i-Series applies analytical intelligence automated features such as mobile phase monitoring for continuous analysis, a mobile phase fl owrate control function, and i-PeakFinder for automatic peak integration. Analytical Intelligence relieves operators from organisational, input and processing works as it allows systems to detect and resolve issues automatically, enabling users to easily review instrument status, optimise resource allocation and achieve higher throughput. It makes lab management simple and enables higher productivity, maximum reliability and better connectivity.


Shimadzu has launched new liquid chromatographs


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