through May 2019. Outcomes that were measured included response rate, depres- sion severity, neurological deficit, physical disability and adverse events experienced by HBOT patients. A total of 27 trials in- volving more than 2,000 participants were identified and reviewed in the analysis.
Researchers deduced that patients in HBOT groups had a higher response rate to depression treatment than patients in control groups. HBOT significantly re- duced Hamilton Depression scores, Na- tional Institute of Health Stroke Scale scores, Chinese Stroke Scale scores and Modified Scandinavian Stroke Scale scores. HBOT also improved Barthel In- dex, which is often used to assess func- tional independence in stroke patients.
In addition, patients with HBOT along with antidepressant treatment achieved superior results than patients who used only antidepressants, and patients who used only HBOT achieved a slightly higher response rate than patients who used only antidepressants. The most fre-
quent side effect of HBOT was ear pain (26 cases).
Studies Support Hyperbaric Oxygen Therapy as a Safe Treatment Option
Another HBOT study, released February 2020 in the journal Case Reports in Pul- monology, explored hyperbaric oxygen therapy as an adjunctive therapy for a nonhealing venous ulcer, a wound on the leg caused by abnormal or damaged veins. The patient in this study was a 65-year-old woman who suffered from systemic scle- rosis, a connective tissue disease that caused chronic, nonhealing skin ulcers that caused significant negative impact to quality of life.
Further complications were presented by pulmonary arterial hypertension, a type of high blood pressure affecting arteries in the lungs and heart. At the study's com- mencement, the patient's nonhealing, lower leg ulcer had caused her mobility to decline to the point where she was confined to a wheelchair and unable to
walk. Doctors administered a total of 30 90-minute HBOT treatments over a five- week period, along with prescribed wound care.
The patient steadily improved over the course of a year until her mobility returned to normal levels. Researchers concluded that HBOT was a successful adjunct therapy in her wound management regi- men, resulting in complete resolution of the venous ulcer and improved quality of life without any adverse effects on her pulmonary arterial hypertension.[xviii]
While hyperbaric oxygen therapy is gener- ally safe and well-tolerated, there are some instances where it's contraindicated. Speak to a trusted health professional to explore if HBOT may be a useful adjunct to your health and wellness routine.
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