Addenda B OO K CH O I CE Blueprint

by Robert Plomin Allen Lane, £20, 2018 Review by Greg Dollman, medical adviser, MDDUS

THE psychologist Robert Plomin argues in his comprehensive new book Blueprint that “genetics is the most important factor shaping who we are”. A keen advocate of ‘nature’ being the design of our individuality, Plomin writes that he does not intend to discard the influence of ‘nurture’, but holds that this is “mostly random”. His work argues that the findings of decades of DNA research will shape the way we predict mental illness, and also influence how we parent and teach.

Plomin summarises: “Inherited DNA

differences are the major systematic cause of who we are. DNA differences account for half of the variance of psychological traits. The rest of the variance is environmental, but that portion of the variance is mostly random, which means we can’t predict it or do much about it.” Plomin clearly wants to start a discussion. He considers heritability (“the one per cent of DNA that differs between us and contributes to our differences in behaviour”) to understand the reason why we are different psychologically, even when environments are shared. He states that while our circumstances will direct outcomes, the genetic differences in personality increase

Crossword 1 2 3 4 5 6

ACROSS 1 Type of lipid, harmful in high levels (11)

7 9 9 10 12 13 15 16 20 19 20 21 18 17 14 11 8 7 Precursors to punchlines (6)

8 Involuntary response to stimulus (6)

10 Instrument with bellows (10) 13 Ignorant (6) 14 Skilful (6) 16 Large measuring spoon (10) 19 Urge (6)

21 Align relative to specified position (6)

22 Device for measuring temperature (11)

DOWN 1 Amounts to be paid (5)

2 Solemn promise (4) 3 Volatile (9) 4 Grain and Sussex town (3)

5 Kojak’s preferred confectionery (8)

6 Instrument for determining angular distance between objects (7)

9 Frozen water (3)

11 Old-fashioned furniture-style music system (9)

12 Gas turbine with a propelling nozzle (8)

13 Nah nah na nah na (2,5)

15 Group of viruses affecting skin/ moist membranes (abbr.) (3)

22 50 crossword.indd 1 28/02/2019 13:26 See answers online 22 / MDDUS INSIGHT / Q1 2019

17 Engine (5) 18 Camping shelter (4) 20 Anger (3)

this happening. So our genetic makeup will determine our response to external events. That is, he argues that genetic research into ‘nurture’ “suggests that environment is imposed on us more actively than passively”.

‘What about the impact of death, illness or divorce?’, I hear you exclaim.

Plomin argues that, genetics aside, any significant environmental factors boil down to chance. They involve random experiences over which we hold little control. As such, Plomin concludes that long- term effects are insignificant, and we inevitably “bounce back to [our] genetic trajectory”. He writes “life experiences matter, but they

don’t make a difference”. He believes even societal factors have little impact on personality. Such assertions are sure to spark debate. Plomin also explores the impact of this theory on individuals, society and psychology. He looks, for example, at predictor scores for mental illness, including schizophrenia and Alzheimer’s dementia, considering how we may use the findings to improve future detection and management. He does acknowledge the dilemma in identifying genetic risk when we are (currently) unable to do anything about it. This book is accessible and thought-provoking.


‘Livingstone’ medicine chest

This medicine chest covered in cow hide was taken by Swedish- American explorer Algot Lane on a 1911 expedition to the Amazon jungle in Brazil. It contains copious amounts of quinine to help prevent and treat malaria and was marketed under the name of the missionary and explorer Dr David Livingstone (1813-1873).

Photograph: Wellcome

Page 1  |  Page 2  |  Page 3  |  Page 4  |  Page 5  |  Page 6  |  Page 7  |  Page 8  |  Page 9  |  Page 10  |  Page 11  |  Page 12  |  Page 13  |  Page 14  |  Page 15  |  Page 16  |  Page 17  |  Page 18  |  Page 19  |  Page 20  |  Page 21  |  Page 22  |  Page 23  |  Page 24