in-cos Cat 30/3/09 17:59 Page 64
64 Advertorial
Sederma has developed PHYTOSONIC
™
a product
designed to combat hypertrophy of adipose tissue
by acting on pre-adipocytes and mature adipocytes
Taking slimming to another level
PHYTOSONIC
™
is from vegetal origin and is derived from the new anti-fat CHROMOCARE
™
technologies of ultrasound cell lysis. PHYTOSONIC
™
is able to selectively Sederma is launching CHROMOCARE
™
, an unprecedented anti-ageing skin
detach hypertrophied adipocytes without destroying them. care based on chromophore mapping.
The properties of PHYTOSONIC
™
enable target slimming not only at To the eye, the appearance of normal human skin under visible light (400-
cellular level but also at tissue level, as demonstrated, for the first time, by a 700 nm) is mainly determined by the concentration and distribution of
three-dimensional reconstructed hypodermis model. melanin, haemoglobin and collagen. There is also a striking difference in the
A clinical study was carried out on 27 female volunteers who applied a concentration and homogeneity of these chromophores between young
cream containing 3 per cent PHYTOSONIC
™
morning and night for 2 and aged skin. CHROMOCARE
™
specifically targets each chromophore in
months. The results obtained showed the efficacy of PHYTOSONIC
™
on order to give the skin a fresher, younger look.
stubborn cellulite with a very significant decrease, ranging from 17 to 69 per
cent, in adipose tissue infiltration into the dermis after 2 months of treatment. Sederma SAS, Stand E500
The ultrasound measurements demonstrated a very significant decrease in
adipose tissue thickness in the thigh and knee. The decreases were 8.5 per Headquarters and Production
cent (up to 18.6 per cent) and 8.2 per cent (up to 20 per cent), respectively. SEDERMA SAS
Therefore, it resulted in a mean reduction in thigh circumference of 1 cm and 29 rue du Chemin Vert
a reduction of up to 2 cm vs. the untreated thigh. 78612 Le Perray en Yvelines cedex France
Tel +33 (0)1 34 84 10 10 Fax +33 (0)1 34 84 11 30
VOLULIP
™
E-mail:
sederma@sederma.fr
Demand for plumper lips is a growing phenomenon as women, who have Web site :
www.sederma.fr
naturally fine lips, wish to give them more sensuality. Furthermore with age,
women try to retrieve attractive lips, which have lost their contour and Subsidiaries
definition, because of dryness, loss in volume and ptosis, and decrease in SEDERMA GmbH
derma density. Herrenpfad-Süd 33 - 41334 Nettetal GERMANY
For this reason, Sederma has now developed VOLULIP
™
an active Tel: +49 21 57 817318 - Fax: +49 21 57 817361
substance containing a plant Portulaca “Kiss-me-quick” extract, associated E-mail:
sederma@sederma.de
with a natural modified matrikine-mimetic peptide, whose main activity is to
stimulate hyaluronic acid synthesis. SEDERMA Inc.
In order to demonstrate the product efficacy and its mechanism of 300 Columbus Circle- Edison NJ 08837 USA
action, several in vitro tests have been carried out following 3 axes, Tel: + (732) 692 1652 - Fax: + (732) 417 0804
stimulation of dermal matrix molecules (collagen 1, collagen 3, fibronectin, E-mail:
marketing@crodausa.com
HSP47), reinforcement of DEJ molecules (collagen 4, laminin 5), Web site:
www.crodausa.com
improvement of hydric sphere (hyaluronic acid, aquaporin 3).
Sederma also carried out 2 clinical studies to prove VOLULIP
™
efficacy on
youth, hydration and lip volume. The first one involved 29 panellists with a
twice daily application of a balm containing 1% Volulip
™
for a month. It
included several complementary methods such as Aeroflexmeter
®
(a device
Before
developed and patented by Sederma which allows skin mechanical
properties to be characterised without any contact, thanks to a compressed
air jet), fringe projections (FOITS) and MoistureMeter-D. The second study
was carried out on a total of 21 panellists to measure re-densification with
After 1 month
an ultrasonor echograph.
The results are very significant. Sederma observed a gain of +13.3 per
cent in firmness, +50.6 per cent in hydration, +10.5 per cent in softness,
+15.1 per cent in volume, +9.2 per cent in curvature (radius of curvature of
the lower lip) and an increase of +19.6 per cent in the surface of the central
area of the lower lip for volunteers with very fine lips. Before After 1 month
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