Figure 1 – Effect of partial replacement of SDPP with yeast* in piglet diets.
In a second trial, 3% usage of SDPP in creep feed was com- pletely replaced with the yeast product in the diets of 24 pig- lets of 21 days of age. This experiment conducted over a 14 day trial period again showed that completely replacing SDPP in creep feed did not reduce the growth performance of wean- ing piglets but encouraged a positive response seen in an improved average daily gain and improved average daily feed intake (Figure 2).
Feed attractant capabilities The peptides and flavour nucleotides in the yeast product make it a good feed attractant. Trials have shown that the product can continue to strengthen feed attractant capabilities and improve feed intake gradually. Additionally, it can be used in piglet diets as an exogenous nucleic acid nutrition source because of the high nucleic acid content inherent within it. During the growth period in piglets, the addition of nucleotide is beneficial to save time and energy for nucleic acids synthesis, and finally promote growth in piglets. In terms of gut protection, nucleic acid in yeast can not only increase the intestinal absorption area by improving the height of intestinal villi (Figure 3), but also promote the growth and development of intestinal cells by affecting intestinal cell divi- sion and differentiation, improving the activity of intestinal enzymes etc., so as to improve the intestinal health.
Immunity enhancement The components with immunity enhancement function in the yeast product tested are beta-glucans, mannans, nucleic acids and peptides. Beta-1, 3/1, 6-glucan can enhance cellular and humoral immunity in piglets, increase antibody level and final- ly enhance the body’s resistance to disease. Mannans can improve villus structure, affect the cytokine con- tent and regulate the immune function of the body in piglets. Also, mannans can improve the local immune response by promoting the secretion of anti-inflammatory factors, regulat- ing intestinal mucosal cell factor and expression of TLR4 gene under the condition of stress and disease. In a 28 day trial with 80 piglets aged 21-days old, the yeast additive replaced 2% of the original 4% of SDPP in the creep feed. When the SDPP was replaced by 2%, the serum immunoglobulin (IgA and IgM) was increased significantly, indicating that partially replacing SDPP with a yeast additive can promote immunity in piglets (Figure 4). Most immune cells cannot synthesise enough nucleotides. Research revealed that the addition of exogenous nucleotides can promote the expression of B lymphocyte and Th cell anti- gen in weaning mice, and promote the differentiation and mat- uration of intestinal lymphocytes. Therefore, when the amount of nucleotides synthesis is limited under stress in piglets, the addition of nucleic acids from yeast can maintain the best function of lymphocytes in weaned piglets. Peptides can pro- mote the development of immune function and promote the immune organ index in early weaned piglets. These research trials have above all, shown the potential of the yeast product to function firstly as a nucleic acid and secondly as a protein source for young animals. This can replace SDPP partially or completely without affecting growth performance in piglets, and ultimately save costs for the producer.
100 150 200 250 300 350
50 0 ADFI （g/d) *GroPro
Figure 2 – Effect of complete replacement of SDPP with yeast in piglet diets*.
100 150 200 250 300 350 400 450 500
50 0
ADG （g/d） ADFI （g/d） SDPP GroPro 431.46 459.84 ADG （g/d) 297.8 307.56 4% SDPP 2% GroPro+2% SDPP 202.8 219.05
304.17 261.9
Figure 3 - The effect of yeast on intestinal villi development in piglets.
ControlYeast additive* *GroPro
Figure 4 - The effect of yeast* and SDPP on humoral immunity in piglets (g/L).
40 50 60 70 80 90
10 20 30
0 IgA *GroPro IgG IgM 22.56b 16.14a 69.35 69.63 CON EXP
45.50b 28.26a
PIGLETS - JULY/AUGUST 2016 19
PHOTO: ANGEL YEAST
g/L
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