EDITOR Tom Mulligan, MSc Tel: +44 1403 220755 Email:
tom@avakado.eu
SALES DIRECTOR Jaymin Amin, BEng Tel: +44 1403 220754 Email:
jaymin@avakado.eu
PUBLISHER Mark Harrington, BSc Tel: +44 1403 220753 Email:
mark@avakado.eu
PUBLISHING CONSULTANT Brian Cooper, MA, CEng
CHINA OFFICE Beijing Oriental Foreland Consultants Co, Ltd Tel: +86 10 84823421 Fax: +86 10 84846103 Email:
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WEBSITE DESIGN Siric Communications Tel: +44 1306 747052 Email:
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WEBSITE
www.avakado.eu/dev/sp2-Magazine/Home
ANNUALSUBSCRIPTION £95.00 UK, £125.00 (US$250.00 or €185.00) overseas (includes postage) sp2
Inter-Active is published six times a year:
January/February, March/April, May/June, July/August, September/October, and November/December by avakado media.
Published by avakado media, Global House, 13 Market Square, Horsham, West Sussex RH12 1EU. UK, Tel: +44 1403 220760 Fax: +44 1403 220761
Printed in England by Manor Creative, Eastbourne, East Sussex, UK ©avakado media, 2012 ISSN 1476-184X
ABC Membership application approved
CONTENTS EDITOR’S PAGE NEWS
MEDICINAL CHEMISTRY
Finding the properties that make successful drugs CONTRACT RESEARCH
Researching co-crystallisation chemistry for improved APIs CHEMICAL SYNTHESIS
4 6
16 20 22
New synthesis methods: unsaturated ketones plus vinyl azides BIOLOGICS
New biologics from glycan-binding decoy protein technology A protein synthesis platform for next-generation ADCs IZB MARTINSRIED/MUNICH
IZB companies: product progress plus new grant awards PEPTIDES & PROTEINS
DRUG DELIVERY
Delivery systems for new vaccine and drug dosage forms DOLS AND PEPTIDE CONFERENCE PREVIEW
26 31 34
Manufacturing deals and technologies for peptide synthesis Microwave technology: a versatile tool for solid phase peptide synthesis
43 44 Cambridge hosts joint DOLS and Peptide Conference 2012 events
sp2 Inter-Active brings you the latest technology and industry updates in drug discovery, development, delivery and manufacture, with enhanced content that includes page links and video. Make the most of these new features by registering to receive the online publication.
March/April 2012 sp2 Inter-Active 3
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