Indeed, he was a master at stimulating
colleagues and fellow researchers to think
afresh. He regularly uncovered faults and
omissions in established work and sought
new approaches and solutions. Here is
brief mention of a few drawn from his
work in microarray analysis: The popular
The ASA
technique of normalization hides more
than it clarifies; false discovery rate meth-
ods are highly unstable in correlated data;
Brings the Library
strong dependencies in gene expression
data erode usefulness of pooling across
to Your Desktop
genes; and since gene expression data
are invariably aggregated over a random
and unobserved number of cells, ignor-
ing this leads to faulty statistical and net-
work analysis. He and his colleagues made
important contributions directed toward
overcoming each of these shortcomings.
He was often appalled at the quality
of refereeing and grant reviewing, feeling
that personal biases often trumped open
discussion and the advancement of sci-
ence. He argued for an open system, as
adopted by Biology Direct.
Andrei had uncanny power of persua-
sion, often motivating people to seek new
directions and attain seemingly unattain-
able goals. He took special care of junior
colleagues—providing inspiration, assur-
ance, and research ideas—and tirelessly
assisted with grant submissions. Although
a person with strong opinions on virtu-
ally every subject—and never shy about
expressing them—Andrei was a gentle
man who genuinely cared deeply about
the people with whom he interacted.
Andrei’s scientific legacy does not con-
sist only of ideas, methods, and results.
Most importantly, he left behind scien-
tific principles and research paradigms
that will guide his coworkers and students
Did you know your ASA membership
for decades to come. He forged them
includes online access to the
through incisive analysis, trial and error,
and excruciating—sometimes heated and
Journal of the American Statistical Association
fierce—debates with his colleagues, dis-
ciples, and coworkers.
Journal of Business & Economic Statistics
On February 26, after sending a
revised manuscript to colleagues late in
and The American Statistician?
the evening, Andrei retired. In the early
morning hours, he suffered a massive
heart attack and died. He will be sorely
Log in at MEMBERS ONLY today to access
missed by his family—wife, Nina, and
your journals! www.amstat.org/membersonly
11-year-old son, Yuri—friends, collabo-
rators, colleagues, and, indeed, the sci-
entific community at large. n
JULY 2008 AMSTAT NEWS 37
Page 1  |  Page 2  |  Page 3  |  Page 4  |  Page 5  |  Page 6  |  Page 7  |  Page 8  |  Page 9  |  Page 10  |  Page 11  |  Page 12  |  Page 13  |  Page 14  |  Page 15  |  Page 16  |  Page 17  |  Page 18  |  Page 19  |  Page 20  |  Page 21  |  Page 22  |  Page 23  |  Page 24  |  Page 25  |  Page 26  |  Page 27  |  Page 28  |  Page 29  |  Page 30  |  Page 31  |  Page 32  |  Page 33  |  Page 34  |  Page 35  |  Page 36  |  Page 37  |  Page 38  |  Page 39  |  Page 40  |  Page 41  |  Page 42  |  Page 43  |  Page 44  |  Page 45  |  Page 46  |  Page 47  |  Page 48  |  Page 49  |  Page 50  |  Page 51  |  Page 52  |  Page 53  |  Page 54  |  Page 55  |  Page 56  |  Page 57  |  Page 58  |  Page 59  |  Page 60  |  Page 61  |  Page 62  |  Page 63  |  Page 64  |  Page 65  |  Page 66  |  Page 67  |  Page 68  |  Page 69  |  Page 70  |  Page 71  |  Page 72  |  Page 73  |  Page 74  |  Page 75  |  Page 76  |  Page 77  |  Page 78  |  Page 79  |  Page 80