American Laboratory Volume 46, Number 5 Contents Life Science
A Matter of Speed: Real-Time PCR for the Rapid Detection of Mycoplasma Contamination by S. Schweizer and A. Scholz .....................................................................................9
Parameters such as sensitivity and time savings are essential for the investigation of mycoplasma contamination.
Life Science
Measuring Absolute Molar Mass Using UHPLC SEC-MALS by S. Kenrick and A. Berges ......................................................................................12
The coupling of multiangle light scattering with UHPLC enables the absolute quantification of a molecule’s molar mass irrespective of elution time and overcomes the limitations associated with conventional UHP-SEC for the characterization of size and composition of aggregates or fragments in a biomolecular sample.
Life Science
On the Cover Crystal of sulfur, resorcinal, and azelaic acid. Polarized light. Original magnification 50×.
Image captured by Dr. John Hart, Hart3D Films and Dept. Atmospheric and Oceanic Sci., University of Colorado—Boulder, CO, U.S.A. Image of Distinction in the 2013 Nikon Small World Photomicrography Competition. For more information, visit
www.nikonsmallworld.com.
Best Practices for the Use of Micropipets by A. Björn Carle, D. Rumery, and G. Rodrigues ........................................................14
The design of air-displacement pipets renders them susceptible to a number of influences from the environment and the operator. Common influences on pipetting accuracy and precision were addressed in this study.
Pharmaceutical
Thorough Risk Assessment Supports At-Scale Process Safety by U. Groth ...............................................................................................................18
This article focuses on obtaining the data needed to develop processes that will help ensure that classic defensive measures are never required, while also improving processes with regard to cost-effectiveness and time-to-reaction.
Life Science
The Importance of an Integrated Informatics Solution for Life Science Organizations and Keys to Successful Deployment
by D. Jansen .............................................................................................................21
Successful deployment of an integrated informatics solution can address issues with ineffective data and technology transfer.
AMERICAN LABORATORY • 2 • JUNE/JULY 2014
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www.americanlaboratory.com
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