12-02 :: February/March 2012

nanotimes

Companies Facts

Moreover, Arrowhead Research and Axolabsin Germany have entered into a Strategic Alliance and Master Services Agreement. Under the terms of the agreement, Axolabs, founded by the principals of former Roche Center of Excellence for RNAi Thera- peutics in Kulmbach, Germany, will provide Arrow- head and its partners first-in-class oligonucleotide optimization, synthesis, and analytics. These services include bioinformatics for siRNA design; lead iden- tification, optimization and characterization; as well as siRNA synthesis and CMC-related activities.

Arrowhead Research has also released a white paper describing the health problem posed by the hepatitis B virus (HBV), the substantial unmet need for chro- nic HBV infected patients, and how Arrowhead’s Dynamic Polyconjugate (DPC) enabled RNAi the- rapeutic in development could potentially address deficiencies of current treatment options.

http://www.arrowheadresearch.com http://www.axolabs.com

B

ASF Venture Capital GmbH has invested $13.5 million in Allylix Inc., a US-based renewable

chemicals company. The BASF subsidiary led a $18.2 million financing round, joined by existing investors Tate & Lyle Ventures, Avrio Ventures and Cultivian Ventures. Allylix has a proprietary techno- logy platform to produce a wide variety of renew- able specialty chemicals, i.e. terpenes and their derivatives, for several industries including flavor and fragrance, food ingredients, cosmetics and other markets. The technology, based on fermentation, allows for the creation of highly pure, renewable

Because ultraviolet (UV) light attacks polycarbonate at the surface, UV protection is most effective when concentrated there. Yet, with traditional compoun- ding of additives it is not possible to concentrate protection at the surface. This limits UV absorber effectiveness in outdoor applications, such as lenses and covers for lighting fixtures, where protection from sunlight is essential to durability and clarity.

compounds that have previously only been available from natural resources in limited quantities.

http://www.allylix.com http://www.basf-vc.de

environmentally responsible way to improve the UV protection of injection molded or extruded polycar- bonate parts. The company has licensed the tech- nology exclusively to Radco Infusion Technologies LLC, for worldwide use.

A

URA™ infusion technology, developed by Bayer MaterialScience LLC, offers a cost-effective and

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