chromatography • spectroscopy 31
systems, including Bridge12’s terahertz gyrotron and transmission line system.
“Te Bridge12 team is very excited about the collaboration with Agilent,” said Jagadishwar Sirigiri, founder. “Our gyrotrons for DNP-NMR systems are turnkey, low-maintenance, and designed specifically for the requirements of the NMR community.”
Te Bridge 12 announcement came shortly after Agilent acquired BIOCIUS Life Sciences, developer of the RapidFire high-throughput mass spectrometry drug-screening platform for the pharmaceutical and biopharmaceutical markets.
BIOCIUS says that its RapidFire drug-screening technology has successfully screened millions of compounds, providing results 10-100 times faster than traditional screening methods. Using high- throughput mass spectrometry and innovative microfluidics, the RapidFire system enables researchers
to gain a fuller understanding of a drug’s biochemical properties, including potential liabilities in drug interactions.
“BIOCIUS’ RapidFire technology gives customers an unsurpassed ability to increase the effectiveness and reduce the cost of drug discovery and compound identification,” said Gustavo Salem, vice president of Agilent’s biological systems division within the company’s life sciences group. “With this technology and the team that developed it now part of Agilent, we can expand our reach in the pharmaceutical and clinical mass spec markets.”
BIOCIUS’ ultra high-speed automated valving, solid-phase extraction, and data-processing systems, when coupled with triple quadrupole or TOF/QTOF mass spectrometers, provide extremely high sample throughput for the biopharmaceutical market.
In other NMR news, JEOL and the Innovation Network Corporation
of Japan (INCJ) have formed a new joint venture company dedicated to the development of next-generation NMR instrumentation.
Flow of technology Te new spinoff, JEOL Resonance, will allow the flow of technology and expertise beyond the boundaries of existing organisational structures through a new ‘open innovation’ concept. A network of collaborators from research institutes, universities, and suppliers, plus an investment of Y1.5b (€12.3m) from INCJ is the spark for a revitalised effort in research and development of advanced NMR systems. Additional funding will come from JASTEC, the only Japanese manufacturer of superconducting magnets for NMR.
NMR is used to determine the structure of molecules by analysing the specific resonance frequency of the nuclei of atoms. NMR excels in the analysis of organic compounds and macromolecules.
Applications are expanding beyond
the domain of pharmaceuticals, biotechnology, food and chemistry into the emerging and exponentially growing new fields of organic electro-luminescence devices, thin film batteries, and alternative energy research. Tis sophisticated instrumentation is comprised of several technologies including digital radio frequency (RF) engineering, superconducting magnets, and NMR probe design, such as the new ultra-fast 1mm 80 kHz magic angle spinning probe for solid state analysis recently introduced by JEOL.
“We expect that by expanding R&D resources and focusing efforts towards producing the next generation of NMR spectrometers, JEOL Resonance will greatly enhance the long-standing reputation of JEOL’s NMR product line,” said Douglas Meinhart, director of JEOL USA Analytical Products.
JEOL Resonance will also continue with development and manufacture of Electron Spin Resonance (ESR) spectrometers.
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