Med-Tech Innovation Materials
requirement with bioactivity being critical for the future development of orthopaedic implants.
References 1. US FDA released reports on 17 July and 13 October 2010.
2. R.F. Coleman et al., “Concentrating of Wear Products in Hair, Blood and Urine after Total Hip Replacement,” Br. Med. J., 1, 527 (1973).
3. J.J. Jacobs et al., “Current Concepts Review: Corrosion of Metal Orthopaedic Implants,” J. Bone Joint Surg. Am., 80, 268 (1998).
4. J.J. Jacobs et al., “Metal Degradation Products: A Cause for Concern in Metal–Metal Bearings?” Clin. Orthop., 417, 139 (2003). 5. Y.M. Kwon et al., “Asymptomatic Pseudotumors After Metal- on-Metal Hip Resurfacing Arthroplasty Prevalence and Metal Ion Study,” J. Arthroplasty, Jun 28 2010 (Epub ahead of print). 6. X. Zhang, PhD Thesis 1992 (Cranfield University), Chapter 8: “Micromechanisms of Deformation.” 7. C. Heisel et al., Bearing Surface Options for Total Hip Replacement in Young Patients,” J. Bone Joint Surg. Am., 85-A,1366-79 (2003). 8. H. Warashina et al., “Biological Reaction to Alumina, Zirconia, Titanium and Polyethylene Particles Implanted onto Murine Calvaria,” Biomater., 24, 21, 3655–3661 (2010). 9. A.S. Greenwald, J.P. Garino, “Alternative Bearing Surfaces: The Good, the Bad and the Ugly,” J. Bone Joint Surg., 83-A, , Suppl 2 Pt 2, 68–72 (2001). 10. C. Hendrich et al., “Highly Crosslinked Ultra Molecular Weight Polyethylene (UHMWPE) Acetabular Liners in combination with 11. 28 mm BIOLOX Heads, in F. Benazzo, F. Falez, M. Dietrich (eds), Bioceramics and Alternative Bearings in Joint Arthroplasty. 11th BIOLOX Symposium Proceedings, Steinkopff Verlag Darmstadt, p.182 (2006).
12. J.M. Martell et al., “Clinical Performance of a Highly Cross- Linked Polyethylene at Two Years in Total Hip Arthroplasty: A Randomised Prospective Trial,” J. Arthroplasty, 18 (7 suppl. 1), 55-59 (2003). 13. L.P. Zichner, H.G. Willert, “Comparison of Alumina Polyethylene and Metal Polyethylene in Clinical Trials,” Clin. Orthop. Rel. Res., 282, 86–94 (1992). 14. L.P. Zichne, T. Lindenfeld, “In-Vivo-Verschleiß der Gleitpaarungen Keramik-Polyetyhlen gegen Metall-Polyethylen” (In Vivo Wear of ceramicsPolyethylene in Comparison with Metal- Polyethylene), Orthopäde, 26, 129–134 (1997). 15. C.R. Bragdon et al., “Steady-State Penetration Rates of Electron Beam–Irradiated, Highly Cross-Linked Polyethylene at an Average 45-Month Follow-Up,” J. Arthroplasty, 21,7, 935–943 (2006). 16. D.W. Manning et al., “In Vivo Comparative Wear Study of Traditional and Highly Cross-linked Polyethylene in Total Hip Arthroplasty,” J. Arthroplasty, 20, 7, 880–886 (2005). 17. T.M. Allen, “Fracture Toughness of Engineering Ceramics,” Progress, No. 9, July 1989.
Dr Xiang Zhang is Principal Consultant, Medical Materials,
Archana Binod-Nair is Technical Consultant,
Mike Salt is Scientist, Advanced Materials, all at CERAM, Queens Road, Penkhull, Stoke-on-Trent ST4 7LQ, UK, tel. +44 (0)1782 764 428, e-mail:
enquiries@ceram.com www.ceram.com/medical
www.med-techinnovation.com April 2011 ¦ 25
Page 1 |
Page 2 |
Page 3 |
Page 4 |
Page 5 |
Page 6 |
Page 7 |
Page 8 |
Page 9 |
Page 10 |
Page 11 |
Page 12 |
Page 13 |
Page 14 |
Page 15 |
Page 16 |
Page 17 |
Page 18 |
Page 19 |
Page 20 |
Page 21 |
Page 22 |
Page 23 |
Page 24 |
Page 25 |
Page 26 |
Page 27 |
Page 28 |
Page 29 |
Page 30 |
Page 31 |
Page 32 |
Page 33 |
Page 34 |
Page 35 |
Page 36 |
Page 37 |
Page 38 |
Page 39 |
Page 40 |
Page 41 |
Page 42 |
Page 43 |
Page 44 |
Page 45 |
Page 46 |
Page 47 |
Page 48 |
Page 49 |
Page 50 |
Page 51 |
Page 52 |
Page 53 |
Page 54