ANALYTICAL AND LABORATORY EQUIPMENT 15


PerkinElmer has debuted an innovative solutions platform for demanding low light level detection applications, called L3D.


Te suite of L3D applications solutions contribute to human and environmental health in a range of applications including confocal microscopy, fluorescence and luminescence, molecular/PET imaging, nucleic acid amplification, particle sizing and research and scientific instrumentation.


PerkinElmer’s growing range of low light level detection solutions leverages the company’s growing range of photon detection technologies and products including avalanche photodiodes (APDs), single photon counting modules (SPCMs), channel photomultipliers (CPMs), and silicon photomultipliers (SiPMs), ideally suited to demanding clinical diagnostics, molecular imaging and analytical instrumentation needs.


Low level light L3D highlights include: new short wavelength-enhanced Si- APD - PerkinElmer’s APDs are ideal for low light level detection applications. Our newest large area short wavelength-enhanced Si-APD is intended for use in demanding molecular imaging and fluorescence detection applications; gigahertz photon detection module (GPDM) - designed for analytical and clinical diagnostic applications under low light level conditions.


Te new GPDM delivers the highest dynamic range available in a single operating mode and very low noise; single photon counting modules (SPCMs) – the company says its cutting-edge SPCMs deliver high photon detection efficiencies (PDE) and very low dark noise for confocal microscopy, particle sizing and time-correlated single photon counting (TCSPC) applications; and silicon photomultipliers (SiPMs) - PerkinElmer recently entered into an exclusive agreement with Max Planck Innovation for the licensing of its ultra-fast, low cross-talk SiPM


technology. Te technology offers record-setting PDE and ultra-short response time. SiPMs offer OEMs a solid state alternative to traditional PMTs in terms of sensitivity and cost.


High content screening Meanwhile, Molecular Devices’ ImageXpress Micro Widefield High Content Screening System is said to offer the ultimate combination of speed and flexibility in a turnkey solution that streamlines research and drug discovery in a fully integrated high content screening environment.


Built on over 10 years of automated imaging experience, the ImageXpress Micro System captures research- quality images with what the company says is the widest range (1-100x) of objective lenses available in an HCS system, enabling users to work at the resolution appropriate for their biology, including small organism, cellular events, or intracellular events. Te system’s best-in-class 100 nm resolution stages precisely locate and identify sub-cellular features, ensuring excellent X, Y, and Z positioning to simplify tracing individual cells during multi-day time-lapse experiments or mapping neuronal outgrowth across multiple tiled images.


Cellular analysis is made easy with the setup wizard that allows any user in the laboratory to acquire and process preconfigured experiments through an intuitive interface.


Industry-leading stage and focus control, coupled with a high-speed laser autofocus option, make the ImageXpress Micro System the fastest, most precise automated CCD imaging station available.


Combined with mature software, the custom designed ImageXpress Micro Instrument outperforms automated microscopes built from off-the-shelf components, providing a robust high content screening (HCS) platform to address both research and drug discovery applications .


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