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SPONSORED > Lab documentation management


Case study: Accelerating drug discovery


D


rug discovery research and development, a discipline once rooted in traditional


methods, is being reshaped by the digital transformation wave. Camurus is a Sweden-based biopharmaceutical company that has gained recognition for its innovative approach in drug development. One of its key advancements is FluidCrystal®, a technology that effectively encapsulates and releases active ingredients. With FluidCrystal®, drug compounds are enclosed in lipid liquid crystalline nanostructures that allow for a sustained release and prolonged therapeutic effects through a single injection. This technology has been successfully applied to address various health issues, including opioid dependence, cancer, and rare diseases such as acromegaly and neuroendocrine tumours. Despite now having about 170 employees, Camurus has achieved remarkable year-over-year growth by forming new commercial alliances and expanding its reach into new markets. The company growth numbers, a 79% increase in net revenue for FY2021, speak for themselves.


Better lab documentation management Nils Ove Gustafsson, VP of Pharmaceutical Development, joined the company in 2018. As he learned more about ongoing processes, he discovered a challenge in locating specific laboratory details within the company. Camurus relied on a paper- based system for documentation, making it tedious to search for experiment-related data using commonly used software such as Microsoft Word and Excel. While the limitation did not, at the time, hinder the company’s ability to scale up, Gustafsson recognised the need for better lab documentation management. As one of his initiatives, he started a


project to find an effective electronic laboratory notebook (ELN) system. After evaluating 19 suppliers, Camurus selected Revvity Signals’ Signals Notebook from a shortlist of six. One of the key decision factors in the selection was the seamless integration of Signals Notebook with


Microsoft Excel, Word, PowerPoint, and other everyday applications. This broad integration, along with the


system’s cloud-native software-as-a- service (SaaS) nature, made the learning curve easier for the scientists who had little experience with ELNs. With more than 40 scientists using it


daily, Signals Notebook has been working smoothly at Camurus. The need for post- implementation assistance from Revvity Signals has even been eliminated. One of the major changes observed since adopting


‘Eliminating tedious and low-value tasks, giving scientists back more time for scientific creative thinking’


the Signals Notebook is the ease of searching prior knowledge and experimental protocols. The ELN collects and links all experiments, providing a comprehensive overview that facilitates collaboration and quick access to the required information. This efficiency has ultimately led to changes in the way work is conducted at Camurus, eliminating tedious and low-value-added tasks, giving scientists back more time for scientific creative thinking. The system has revolutionised how the company operates in the lab and has been


well received by new employees due to its intuitiveness, ease of use, and modern user experience. It should serve as an encouragement for biopharmaceutical companies still relying on paper-based systems to consider implementing an ELN, as hefty rewards can be gained from a relatively small effort in procurement, training, and implementation.


Intuitive user interface As a cloud-native SaaS ELN, Signals Notebook stands out as the only solution covering a comprehensive set of scientific use cases in biology, chemistry, formulations, analysis, and more. It offers an intuitive user interface, enhanced collaboration, improved R&D workflows, and lab automation. The system enables informed decision-making through data re-use optimisation and can be a central component of any scientific digital transformation strategy. The adoption of Signals Notebook has the potential to revolutionise lab operations for pharma R&D companies by improving efficiency, collaboration, and data management. As a gateway to digital transformation, cloud-native SaaS can empower both small and large companies to streamline their scientific R&D processes. By eliminating tedious tasks, these modern tools give back precious creative time to scientists, enabling them to concentrate on their core research. The adoption of such technology is not just a step forward, it’s a leap toward a more innovative and efficient future for scientific discovery. SCW


For more information about the Signals Electronic Lab Notebook, visit: https://revvitysignals.com/


SCIENTIFIC COMPUTING WORLD


Summer 2023 Scientific Computing World 21


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