Vibrating Microtomes 7000smz-2 and 5000mz-2


Top-of-the-range, high precision, vibrating microtomes...the finest slicers in the world for all specimen preparation.


Features at a Glance • Z-axis blade adjust minimizer


• Custom blade holder with angle set to user requirement


• Set START and STOP position for blade travel


• Vibration speeds from 50 to 120 Hz • Amplitudes from 0.5mm to 2.25mm


• Controlled blade advance at 10 microns per sec.


• Ice water bath easily removed for cleaning • Optional LED light source • Optional magnifier for clear observation


• Optional stereoscope, choice of x5-x10 fixed or x10-40 zoom for optimal observation


On the 7000smz-2 additional features: • Includes a Z-axis calibration device • Choice of manual or automatic operation


• Auto programming by storage of the first slicing speed and distance profile


The 5000mz-2 is a very competitively priced high precision unit with a z-axis deflection of only 1-2 microns and a blade advance controllable to 10 microns/sec. The 7000smz-2 unit has a Sub-Micron z-axis deflection and a blade advance controllable to 10 microns/second. On both units the section thickness step size is 0.001mm. All types of sectioning is possible including sectioning for visual patching of neurological tissue, heart, and lung, and much more....


Options


Temperature Controlled Standard Tissue Bath Model 7610-A


The 7610-A Tissue Bath Cooler Unit is intended for use with our 7000 and 5000 range of vibrating microtomes. Unfixed brain slices sectioned at 4°C give better tissue preservation and are viable for longer in-vitro recordings. Additionally, some enzyme histochemical techniques give better staining results when sectioned at low temperatures.


The 7610 Series coolers use “Peltier” thermoelectric elements. The stainless steel


tissue bath and mount are detachable to allow sterilization by autoclave if required.


The equipment comprises of a mains operated control unit, cooling element, tissue bath and specimen holder. The control unit houses a power supply and temperature control circuitry. The cooling element assembly consists of thermoelectric “Peltier” elements, temperature feedback sensors and a cold water fed heat exchanger.


Current from the power supply flows through the thermoelectric elements, which act as heat transfer units. Heat is drawn off, cooling the solution in the tissue bath. The heat generated by this process is removed by the water


supply fed through the heat exchanger. The unit uses a proportional temperature control algorithm to maintain temperature stability. This will hold the bath temperature to within 0.5ºC of the temperature set point. There will, however, be a small variation in temperature vertically through the bath. Experience will show the best temperature to be set for any given requirement and ambient temperature.


Product Specifications Display Resolution


Temperature Accuracy Temperature Range* Voltage Requirements


Power Rating Inlet Fuse Rating 0.1°C +/- .5°C +8°C to 0°C*


230V 50Hz or 115V 60Hz


60W 2A


* Note that the actual temperatures achievable will be dependent upon the solutions used and local temperature conditions


The effect of excessive Z-axis deflection on the health and viability of the tissue preparation has been much discussed since the publication of Jonas et al (2003) and the 7000smz-2 will now deliver perfect sections every time with sub-micron Z axis deflection across a wide range of vibration speeds and amplitudes. The affordable 5000mz-2 offers almost the same features with Z-axis deflection of 1-2 microns at all vibration speeds and amplitudes, which is less than most other microtomes on the market.


The all-new user interface is both easy to use and versatile. The 7000smz-2 and the 5000mz-2 offer similar operation at the press of a button. The versatility includes simple operation at the push of a button or a range of changeable and programmable parameters and a menu enables the settings of your own preferences.


The 7000smz-2 also gives you longevity of performance, in other words it not only gives submicron performance out-of-the-box but the advance vibrating mechanism does not contain bearings and other components subject to wear. Consequently it will retain the sub-micron Z-axis deflection performance for years to come, giving you consistency in your biological preparation.


Tissue cooling is accomplished by the use of either an ice-water bath or an electronically controlled thermoelectric cooler. Other options include a LED cold light source and a magnifier or a stereoscope for clear observation whilst slicing.


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