Ethicon have the first and only sutures with Antibacterial Protection recommended for use in the NHS by NICE Medical Technologies guidance*1
Nearly 30% reduction in the risk of surgical site infection1
Potential environmental benefits to the NHS1
Cost-saving by an average of £13.62 saving per patient1
MONOCRYL Plus reduces suture TM 99.99%
colonization by common SSI pathogens by 99% up to 99.99% as compared to non-antimicrobial sutures §†‡
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*As of August 2021. §Tested in a 2-0 MONOCRYL™ Plus suture. †Log Reduction - Staphylococcus aureus 3.69, Staphylococcus epidermidis 1.84, MRSA 3.10, MRSE 4.92, Escherichia coli 4.54, Klebsiella pneumonia 3.64 - Log Reduction 1 = 90% reduction, Log Reduction 2 = 99% reduction,
Log Reduction 3 = 99.9% reduction, Log Reduction 4 = 99.99% reduction. ‡The study was executed following protocol 100883589 and 100207824 Test Method for Bacterial Attachment rev 1. Based on a two-sample t-test, efficacy was demonstrated for Staphylococcus aureus (p-value 0.000), Staphylococcus epidermidis (p-value 0.000), MRSA (p-value 0.000), Escherichia coli (p-value 0.000), and Klebsiella pneumoniae (p-value 0.000) using 10% Trypticase Soy Broth (TSB). Efficacy was not observed for MRSE using the same conditions (10% TSB). MRSE is a slow growing bacterium and the recovery from control sutures was in the range of 3.5-4.24 log CFUs, which is 1-2 logs lower than other challenge bacteria, suggesting the media used (10% TSB) may not be suitable for this slow growing bacterium. It was thought that increasing concentration of TSB from 10- 50% would provide additional nutrients and hence support robust growth of the bacterium. The study was repeated with inoculum prepared in 50% TSB and results are reported (p-value 0.000). 1 © NICE 2021. MEDICAL TECHNOLOGY GUIDANCE: PLUS SUTURES FOR
PREVENTING SURGICAL SITE INFECTION. Available from:
nice.org.uk/guidance/MTG59 Accessed on: 28 June 2021. All rights reserved. Subject to Notice of rights. NICE guidance is prepared for the National Health Service in England. All NICE guidance is subject to regular review and may be updated or withdrawn. NICE accepts no responsibility for the use of its content in this product/publication. | Johnson & Johnson Medical Limited Baird House, 4, Lower Gilmore Bank, Edinburgh, Scotland, EH3 9QP. Please refer always to the Instructions for Use / Package Insert that come with the device for the most current and complete instructions. © Johnson and Johnson Medical Limited 2023 237145-230105 UK.
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