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laboratory informatics


collaborations with clients to expand capabilities, Lemon adds. ‘Back in 2008 we were tasked by what is now AbbVie to build an enterprise-scale assay requesting solution, which would address the increasing trend for outsourcing activities such as sample testing and compound storage. Te soſtware that Te Edge developed allows project teams to submit and track assay requests to and from internal departments, collaborators and contract service providers. Tese capabilities are embodied in the BioRails PTO (project tracking and optimisation) module, which allows users to plan, request and track both in house and outsourced activities, and follow and manage workflows within and between departments and contract or partner organisations.


Hybrid inventory support BioRails PTO is complemented by BioRails Inventory, a dedicated plate and vial-based inventory module for managing activities from plate registration, to creating plates, transferring materials, and managing inventory for both solids and liquids, between and within CROs and their clients. ‘Traditional inventory systems were struggling because they were only designed


to work in house. We have developed BioRails Inventory in collaboration with our clients, and in particular with the animal health company, Zoetis – which had already purchased BioRails for assay requesting – as a hybrid system that enables the ordering of compounds from an externally managed powder store, and then the receipt, handling, dissolution, and dispensing of these compounds, in house.’ BioRails PTO and BioRails Inventory


have allowed Te Edge to develop close relationships with a number of CROs as well as large pharma. ‘Our aim has been to connect CRO with pharma and biotech clients, and facilitate the seamless storage, transitioning and management of inventory, assay requests and workflow data and results between those parties.’


Connecting with LIMS BioRails can also connect with an existing informatics infrastructure and bridge the gaps leſt by systems such as LIMS, Lemon continues. ‘LIMS is very sample orientated, and if it’s not a sample that you are testing then a LIMS doesn’t know what to do with it. In contrast, BioRails doesn’t care what you are testing. It could be a sample, or a compound, or an animal, or a target. You


can configure BioRails to store whatever test data you want, and use it to request that test and then track its progress. We could, for example, use a LIMS as a source of sample information, then employ BioRails to request and delegate the execution of an experiment, and run the experiment through an ELN. Some of our clients call BioRails a kind of ‘grout’, because it fills in all the gaps.’


Focus on core disciplines Since its inception in 2005 Te Edge has been totally self-funded, and has grown to a personnel base of 20 ‘brilliant’ scientists and technical experts, Lemon states. ‘We have about 50 clients globally, and among those we are working with four of the world’s top 10 pharmaceutical companies. We aim to continue to focus on our core discipline of biology, and extension into inventory support, assay requesting and planning. What we are not claiming to be is a one- stop-shop. Our growth has been organic, and we aim to build on our achievements and to increase our visibility and sales and marketing activities. Ours is a different business model that is based on innovation born of collaboration with clients. Hopefully that will continue to work well for us as we grow our client base.’l


The greatest discoveries start with a single question The greatest discoveries start with a single question


Leading Bio/Pharmaceutical companies and CROs use BioRails for project tracking


Leading Bio/Pharmaceutical companies and CROs use BioRails for project tracking


Assay requests, experiment planning and project cascades Workflow, productivity, collaboration and knowledge management DMPK, Pharmacology, ADME, Toxicology, in vivo, in vitro... Modern solutions: desktop, intranet, cloud


Assay requests, experiment planning and project cascades Workflow, productivity, collaboration and knowledge management DMPK, Pharmacology, ADME, Toxicology, in vivo, in vitro... Modern solutions: desktop, intranet, cloud


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