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American Laboratory Volume 46, Number 4 Contents Pharmaceutical


Improving the Crystallization Process for Optimal Drug Development by M. Collazo, S. Vaezeslami, and S. Burl ..................................................................11


This article describes the use of automated liquid handlers to optimize the initial hits and the process required for optimal crystal formation.


Conference Review


Focus Sharpens on Miniature Optical Spectrometers at Pittcon® by M. Wilkinson ........................................................................................................18


Several innovations on display at Pittcon® promise to further miniaturize and reduce the cost of future optical spectrometers.


Conference Review


On the Cover Specimen: Human lung fibroblast showing intracellular proteins. Technique: Epifluorescence


microscopy, 20× objective. Image captured by Dr. Ankur Singh, Cornell University, Ithaca, NY, U.S.A. Honorable Mention in the 2013 Olympus BioScapes Digital Imaging® Competition. For more information, please visit www.olympusbioscapes.com.


Sample Processing at Pittcon® 2014 by R.L. Stevenson .....................................................................................................21


This review describes new automated sample processing systems that improve data quality and save time.


Life Science


LIMS-BPMS Coupling: A Novel Approach for Flexible End-to-End Workflow Automation in Life Science Laboratories, Part 1


by S. Holzmüller-Laue, B. Göde, and K. Thurow ........................................................26 Part 1 of this two-part paper features a new approach to workflow automation.


Conference Review


Mass Spectrometry—The Quest for Ionization Improvements: Notable New MS Products at Pittcon® 2014


by B. Musselman ......................................................................................................30


A number of new MS technologies were introduced this year at Pittcon, as were new uses for GC/MS and LC/MS.


AMERICAN LABORATORY • 2 • MAY 2014


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