Conference Review
by Brian Musselman
Mass Spectrometry—The Quest for Ionization Improvements: Notable New MS Products at Pittcon® 2014
S
itting here watching March Madness reminded me of the new instrumenta- tion presented at Pittcon® in Chicago. Not one, but two, mass spectrometer prod- ucts were awarded a Pittcon Editors’ Award, including the first truly integrated capillary electrophoresis/mass spectrometer (CE/MS) and a compact LC/MS designed to enable simplifi ed operation in a low-cost instrument. With the conference’s move to Chicago this year, it seemed that the number of mass spec- trometry talks and sessions increased, with special sessions in forensics and food analy- sis showing new uses for GC/MS and LC/MS. New technologies presented at the show are listed alphabetically by company for your reading pleasure.
AB SCIEX (Framingham, MA; www.absciex. com): Introduced the CESI 8000, a capillary electrophoresis system with a dedicated elec- trospray ionization interface connection to AB SCIEX LC/MS instruments. The interface does not use a sheath liquid like earlier ap- proaches; instead, an electrospray solvent is added post-CE column to promote ionization of the molecules. The CESI 8000 system is the fi rst CE-related product launch from AB SCIEX. The company obtained the CESI technol- ogy through combining the CE business of Beckman Coulter Life Sciences (Indianapolis, IN;
www.beckmancoulter.com).
Advion (Ithaca, NY;
www.advion.com): Announced improved versions of its compact expression CMS mass spectrometer. The ex- pressionL
has a 2000-Dalton mass range; this is
signifi cantly higher than its original CMS, which has been upgraded to become expressionS
. The
interface of these CMS units to LC, fl ow reac- tors, supercritical fl uid chromatography (SFC), preparative LC, and CAMAG’s TLC-MS Interface (Muttenz, Switzerland;
www.camag.com) are highlighted in the company literature.
Analyze IQ (Dublin, Ireland;
www.analyzeiq. com): Presented SmartSearch™, a program that allows you to search rapidly and accurate- ly through a library of spectra to identify the best matches for unknown spectra, enabling you to answer “what is this?” questions easily and reliably. The program provides accurate
the ESI/MS. For its MALDI-TOF product line, the autoflex™ speed offers faster 2-kHz Smartbeam Laser sampling speed for use in reducing the time requirement for applications such as biomarker discovery, imaging, and drug and metabolite tissue distribution.
The company also introduced its Dash Reporting Software for processing GC/MS and LC/MS data. The program allows its users to “draw” report elements then sort, filter, resize, and format those drawings to generate flex- ible customized reports for lab clients.
The number of mass spectrometry talks and sessions increased, with special sessions in forensics and food analysis showing new uses for GC/MS and LC/MS.
spectrum matching algorithms to let you iden- tify a ranked set of spectra that are the closest matches for a spectrum of interest using an innovative new Spectral Euclidean Distance algorithm that was developed for the product.
Bruker Daltonics (Billerica, MA;
www.bruker. com): After introducing three new MS systems this year, the company launched a next- generation GC-APCI II interface for coupling a GC transfer line to any Bruker electrospray ionization (ESI) mass spectrometer. The use of this flexible interface line means that the GC can be easily mounted and dismounted within minutes without requiring careful alignment and positioning of the GC in close proximity to
AMERICAN LABORATORY • 30 • MAY 2014
BSSN Software (Darmstadt, Germany; www.
bssn-software.com): Displayed its new Contract Research Manager software solution, which enables management of relationships with external partners, such as contract research organizations (CROs) and contract laboratories. The company utilizes AnIML tools and instru- ment fi le converters to permit more effi cient exchange of data between organizations.
Diablo Analytical, Inc. (Antioch, CA; www.
diabloanalytical.com): Exhibited MS Sensor 3.0 Process Analysis Software, which permits real- time display in graphical and tabular format. The software enables the use of an Agilent 5977 MSD for continuous process analysis.
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