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Issue 128 February/March 2013 CONTENTS

Laboratory Informatics News and products

All part of the service

Contract research organisations (CROs) demand sophisticated informatics systems, as Beth Harlen discovers

Pittcon preview As Pittcon celebrates more than 60 years, we present a round-up of the exhibitors

Statistical Science Statistical software reviews The joy of text

Felix Grant investigates the complexities of textual analysis

High-Performance Computing News and products

The processing challenge

John Barr weighs up the contenders in the battle for processor dominance

The power behind pharmaceuticals

Industry experts discuss the use of HPC in drug discovery

Modelling and Engineering News and products

Body of evidence

Beth Harlen reports on how modelling and simulation tools are changing the face of medical research

Speed, integration and interactivity

Siân Harris finds out about some of the developments within pharmaceutical modelling

Resources Suppliers’ directory

Inside view

36 38


30 32


22 24

16 18


4 6

Making a discovery

Tere is one clear theme running throughout this issue of Scientific Computing World, as we turn our attention to the field of drug discovery – and what a complex field it is. As pharmaceutical companies continue the outsourcing of their R&D efforts, contract research organisations (CROs) are playing an increasingly critical role in the drug development pipeline. As such, they need top-notch informatics solutions that ensure the efficiency, quality and traceability of the data being produced. More details can be found on page 6. Although relatively new within the

pharmaceutical industry, the use of HPC is already having a considerable impact (p.28), and Siân Harris reports on how the latest molecular modelling techniques are further speeding the process (p.34). Rounding off this issue, we present a preview of Pittcon (p.12), John Barr's insight into the battle between Nvidia and Intel for processor dominance (p.24), Felix Grant's investigation into textual analysis (p.18) and my feature on biomedical modelling (p.32).

Beth Harlen Editor


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