GLAL_I_50_S1_COVER.qxd 10/6/09 2:24 PM Page 2
New Y 10017.NY ork,
Annual Subscription, V
the euro rate applies in mainland Europe and the USD rate applies to the rest of the w
subscriptions are payable in advance and all rates include postage. Journals are sent by air to Europe,
and Australasia. Subscriptions are entered on an annual basis,
money order, National Giro, or credit card (American Express,
Subscription and single issue ordering information
Customer Services, Informa, Sheepen Place, Colchester,
or Mastercard). isa,V
Essex CO3 3LP
(0)20 7017 4614. E-mail: healthcare.enquiries@informa.com
Back issues
Informa Healthcare retains a three year back issue stock of journals. Older v
Service Company, 11 Main Street, Germantown, NY 15526, USA to whom all orders and inquiries should be addressed.
537 4700. Fax: +1 518 537 5899. E-mail: psc@periodicals.com. Web:
agent to arrange for delivery of print issues.
Advertising, reprint, and translation inquiries
Inquiries regarding advertisements, article reprints, or translations should be directed to Lee Vasey. Tel: +1-212-520-2744. E-mai
journal-ads@informa.com
The print edition of this journal is typeset by KnowledgeWorks Global Limited, Chennai, India, and printed by Latimer
Plymouth, UK. Production Editor: Claire Summerfield
Copyright 2009 Informa Healthcare USA, Inc. All rights reserved. No part of this publication may be reproduced,
transmitted, or disseminated in any form or by any means without prior written permission from Informa Healthcare. Informa
Healthcare grants authorization for individuals to photocopy copyright material for pri
+1 518el:T
vate research use on the sole basis that
stor
rand,T
requests
for such use are referred directly to the requester’s local Reproduction Rights Or
alsPeriodicicial stockists:folumes are held by our of
http://www.periodicals.com.html
Claims
Printed copies of the journal are provided as a free supplementary service accompanying an online subscription. Customers who d
not receive their free printed copy can normally request a replacement which will be fulfilled at our discretion. Claim fulf
subject to the availability of stock and reliability of mail services in particular geographic areas. Claims for missing copies must be
lodged within 3 months of initial publication. For customers receiving print copies through a subscription agent,
ganization (RRO),
theplease contact
ent isilm
such as the Copyright Cleara
ed,
nce
Center (www.copyright.com) in the USA or the Copyright Licensing Agency (www.cla.co.uk)
o
+44ax:+1 800 997 3892 or +44 (0)20 7017 5540. Fel:TUK. ,
nalinternatioayment may be made by check,. PJanuary to Decemberi.e.,
nJapaIndia,xico,MeCanada,
Allorld.
enue,vAanderbilt V52 published monthly (total 12 issues) by Informa Healthcare,wed journal,vie-reis a peer
TIONSUBSCRIPTION INFORMA
Leuk ymphomaemia & L
Institutional
Corporate
A subscription to the Journal includes access to the online edition for concurrent users across a local area netw
available upon request.
For more information,
y isopcA print ork.
6785€£5995$8480
3390€£3000$4240
2009olume 50,
visit the journal’
For a complete and up-to-date guide to Informa Healthcare’
http://catalogue.informahealthcare.com/
Leukemia & Lymphoma (USPS permit number 021 187) is published monthly
Periodicals postage paid at Jamaica, NY by US Mailing
th
149-35 177orldnet Shipping USA Inc.,Wc/o Air Business,Agent
The 2009 US institutional subscription price is $4240..
s journals and books publishing programs please visit:
.informahealthcare.com/lalhttp://wwws website:
Jamaica, New York, NY11434. US Postmaster:
149-35 177
th
Street, Jamaica, New York, NY 11434.
The sterling rate applies in the UK,
orldnet Shipping USA Inc.,Wc/o Air Business Ltd,Please send address changes to
Street,
in the UK. This
l:
authorization does not
extend to any other kind of copying by any means, in any form, and for any purpose other than private research use. The publisher
assumes no responsibility for any statements of fact or opinion expressed in the published papers. The appearance of advertising in
this journal does not constitute an endorsement or approval by the publisher, the editor, or the editorial board of the quality or value
of the product advertised or of the claims made for it by its manufacturer.
Abstracting and indexing services
Leukemia & Lymphoma is abstracted in: Science Citation Index, CML LEUKAEMIA AND LYMPHOMA, Current Contents/Life
Sciences, Current Contents/Clinical Medicine, EBSCO
laboratory diagnosis,
(SUB 09/09)
y of patients with these disorders.clinical care and therap
cal andvide an important reference source for physicians and scientists who deal essentially with the cliniThe journal will proield. f
to thisances in molecular genetics as applied vided on the basic issues and advan update is proand postgraduate teaching. In addition,
nsw and interesting data for cliniciavide neel and provwhich are nocorrespondence to the editors are also accepted on all topics,
and molecular immunology of hematologic malignancies; the journal aims at a strong clinical-pathologic correlation. Letters and
ytogenetics and cellularcultrastructure,,ytologyc,pathologylaboratory diagnosis,epidemiological studies and outcomes analysis,
ws on clinical and therapeutic practice,vieis an international journal that publishes full-length papers and reymphomaemia & LLeuk
Aims and Scope
orma.comDidi.peng@infE-mail:
UK
EC2A 4LQLondon,eet,aul Str69–77 P
eorma HealthcarInf
elephone HouseT,Managing Editor
engc/o Didi P
ymphomaemia & LLeuk
ice:fEditorial Of
idence in the research enterprise.enhances public conf
andresearchers and patients,acilitates the dissemination of information among clinicians,gistration of all clinical trials fThe re
g)..icmje.orSubmitted to Biomedical Journals (http://www
see ICMJE Uniform Requirements for Manuscriptsor more information,.who.int/ictrp/en/). FPlatform (ICTRP) (http://www
istrygrials ReTWHO International Clinical please see the gistries that meet all of these requirements,or a list of reganization. For
it-profgistrants and managed by a not-fore revbe open to all prospectige,gistry must be accessible to the public at no charThe re
gistered in a public repository at their inception and prior to patient enrolment.2006 be re
ated after Jan 1vrequires that all clinical trials actiymphomaemia & LLeuky published in an ICMJE Editorial in June 2007,the polic
oIn accordance with the guidelines published by the International Committee of Medical Journal Editors (ICMJE) and the changes t
gistry:Rerials Clinical T
.ypreferential rate of $25.00 per copCopies of the Journal can be purchased at the authors’
ed.vwhen proofs are recei
®
ymphoma). Reprints of articles published in this journal can be purchased through RightslinkemiaLLeuk
orld.com/w.informae free online access to their article through the journal website (http://wwwvauthors will recei
spondingfprints and reprints of articles published in this journal can be purchased once the article has been published online. CorreOf
fprints and Reprints:Of
ute to the associated costs. contrib
sudget will only be considered on condition that authorxcess of the journals bs online edition. Colour reproduction in ejournal’
theigure submitted as a colour original may appear in colour within y fAnwith respect to colour reproduction at submission stage.
icefAuthors should consult the editorial ofance. wThe journal has a limited number of free colour pages within its annual page allo
es:gColour Char
sharing and dissemination of scholarly information.
garding the freethe STM agreement reand respect the spirit of,Inc. are signatories of,Please note that Informa Healthcare USA,
yright material from other sources.permission to reproduce cop
es responsible for obtainingAuthors are themselvyright for full details. orld.com/smpp/authors_journals_copw.informahttp://www
atto referred are policies These documents. policies rights Informathe under rights other of number a retain
thorsAuw that its use is properly authorised. ied so that our records shois notifand that Informathe original source of publication,
en to the Journal asvwledgement is givided that acknopropublication without prior permission from Informa,afterwhere article else
theuse of course,,Authors mayto the widest possible readership in print and electronic formats as appropriate. course the Journal,
and ofyright protection and to disseminate the article,This enables us to ensure full copInc. to Informa Healthcare USA,abstracts,
includingyright or license the publication rights in their articles,It is a condition of publication that authors assign copCopyright.
Author Centre.irst create an account. Once a user is logged onto the site submissions should be made via the w users should fNe
http://mc.manuscriptcentral.com/glal.
s Manuscript Central site’ymphomaemia & LLeukAll submissions should be made online at
.informahealthcare.com/lalhttp://www
s website for a complete style guide;please visit the journal’Before preparing your submission,
ymphomaSubmitting a paper to
, SciSearch, Research Alert, Medical Documentation Service, Index
Medicus/MEDLINE/PubMed, Excerpta Medica, Current Awareness in Biological Sciences (CABS), Current Sciences Ltd., InfoMed
Ltd., Reference Update, SUBIS, Oncology Information Service, Inpharma Weekly, Mediascript; Chemical Abstracts Service; Revue
Roumaine de Medecine Internet and SIIC Data Bases.
Disclaimer
Whilst every effort is made by the publisher and Editorial Board to ensure there are no inaccuracies in this Journal, statements, opinion
and data appearing in the articles and advertisements herein are the responsibility of the authors and advertisers concerned. The Editors
and Publisher disclaim an
LLeukemia &
y responsibility or liability for such material.
(SB 01/08)
Page 1  |  Page 2  |  Page 3  |  Page 4  |  Page 5  |  Page 6  |  Page 7  |  Page 8  |  Page 9  |  Page 10  |  Page 11  |  Page 12  |  Page 13  |  Page 14  |  Page 15  |  Page 16  |  Page 17  |  Page 18  |  Page 19  |  Page 20  |  Page 21  |  Page 22  |  Page 23  |  Page 24  |  Page 25  |  Page 26  |  Page 27  |  Page 28  |  Page 29  |  Page 30  |  Page 31  |  Page 32  |  Page 33  |  Page 34  |  Page 35  |  Page 36  |  Page 37  |  Page 38  |  Page 39  |  Page 40  |  Page 41  |  Page 42  |  Page 43  |  Page 44  |  Page 45  |  Page 46