LABORATORIES
AUTOMATED MICROSCOPE CONTROL DESIGN CONSIDERATIONS
For a range of applications, from blood analysers through to semiconductor capital equipment, automated microscopes achieve image gathering that is both faster and significantly more accurate. To optimise the clarity and detail of image capture, an automated microscope’s motion control architecture must synchronise an XYZ axis system with optimum precision. Gerard Bush, engineer at motion control specialist INMOCO, explains the key considerations in automated microscopy motion design.
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ital to applications in life sciences and across industry, automated microscopy demands a high level of motion control precision to optimise the observation of samples. Operating on the same
principle as a three-axis gantry over X, Y, and Z axes, positioning accuracy is measured in microns or even nanometres.
The X and Y axes control the movement of the optical system to view specific regions of the sample, and a relatively small error in positioning can lead to imaging artifacts or missed regions in a scan. The Z-axis, responsible for focusing the image, doesn’t demand the same exacting level of precision due to the microscope system’s depth of field and range of positions where the image remains in focus, yet the need for resolution remains important. To achieve this level of precision, premium grade automated microscopes typically integrate linear direct drive brushless DC motors. While the control electronics of a brushless DC set-up optimises precision, a direct drive coupling minimises the challenges of backlash, friction, and mechanical compliance that can disturb smooth and controlled motion. Piezo motors, which expand or contract when electrically stimulated to generate motion, can also be integrated to achieve high levels of precision and virtually silent operation. For more cost-effective designs, rotary brushless DC motors with a ball screw are an alternative, or even stepper motors.
Summer 2025 UKManufacturing
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