Company insight
A game-changer for clinical trial design
Cytel, a leading provider of cutting-edge analytical solutions, quantitative methods, and innovative statistical software for the life sciences industry, has just unveiled an innovative platform that represents a significant advancement in the field of clinical trial design and simulation: East Horizon™. Building on more than 30 years of experience, Cytel has developed a cloud-native, intuitive platform that promises to significantly accelerate the drug development process, making clinical trials more efficient, cost-effective, and reliable. Clinical Trials Insight hears from Kevin Trimm, chief product officer and Aniruddha Deshmukh, VP of Software Engineering at Cytel to find out more.
he East Horizon™ platform is a culmination of Cytel’s long history of providing statistical solutions and consulting services for the pharmaceutical sector. Known for products like East®, which has long been the gold standard in adaptive clinical trial design, Cytel has expanded its capabilities with this modern, comprehensive platform that brings cutting-edge methodologies to the fingertips of researchers and pharmaceutical companies. The launch of the East Horizon platform represents the next chapter in Cytel’s evolution. “The East Horizon platform brings together all of the innovation that we've developed within the space of clinical trial design over the years into a singular platform,” explains Kevin Trimm, chief product officer. This new platform integrates advanced technologies and methodologies into a single, user- friendly platform, positioning itself as the next-generation clinical trial design software. By consolidating multiple tools into one cloud-native platform, it offers a seamless workflow that helps pharmaceutical companies design more optimal trials, increasing the chances of success in clinical development. “That’s the biggest implication of the platform – promoting the adoption and use of these advanced methodologies and designing trials that ultimately result in medicines getting to market much faster.”
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The East Horizon platform, revolutionising clinical trials with adaptive design, powerful simulations, and streamlined workflows for faster, smarter drug development.
Simulate multiple outcomes The East Horizon platform offers a significant advantage by enabling pharmaceutical companies to select the optimal clinical trial design for their needs through Explore, one of the tools within the platform. “Explore’s innovation lies in its ability to enable users to simultaneously evaluate multiple designs under multiple operational scenarios on a large scale,” adds Trimm. Unlike traditional methods, where trial designers would simulate one design at a time based on a limited set of assumptions, the East Horizon platform lets users simultaneously evaluate a wide range of design scenarios.
For instance, a clinical trial team can now simulate how a drug might perform under different patient response scenarios, varied patient enrolment rates, or in different geographical regions. The
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East Horizon platform’s powerful simulation capabilities enable users to generate tens of thousands of potential trial models, allowing them to identify the best trial design based on factors such as statistical power, duration, and cost. “The East Horizon platform gives a huge boost to productivity because now [clinical trial teams] can view the entire design space at a glance and use the tools within the platform to quickly identify the most optimal design that either reduces the trial duration, saves costs, or improves other aspects of trial design,” says Aniruddha Deshmukh, VP of Software Engineering. By offering a broad range of potential designs, the East Horizon platform minimises the guesswork that typically accompanies trial planning. It provides a more robust, data-driven approach to decision-making, ultimately helping pharmaceutical
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