NanoSurface Cytostretcher & Cytostretcher-LV


All-in-one cell stretching instruments for Biomimetic Experiments


Overview


Understand the Effects of Mechanical and Microenvironmental Cues


The NanoSurface Cytostretcher allows researchers to investigate both tissue-level mechanical strain and microenvironmental cues at the same time.


The Cytostretcher family of instruments is a powerful and easy-to-use integrated solution for cell mechanics research. The Cytostretcher and Cytostretcher-LV empower you to gain new insights into the relationship between the cell and its microenvironment – important for nearly all mammalian cell types. NanoSurface's patterning technology provides structural cues that recapitulate the native ECM within flexible stretching chambers. The included NaOMI software provides total experimental control in a clean, intuitive interface.


The flexibility and power of the Cytostretcher family of instruments ensures that every cell stretching experiment can be implemented with ease and precision.


Biomimetic surface architecture meets bulk mechanical strain


Investigate multi-scale mechanical stimulation


NanoSurface nanopatterned culture surfaces provide a cellular microenvironment that mimics the aligned architecture of the native extracellular matrix, promoting cellular structural and functional development. The NanoSurface Cytostretcher integrates flexible NanoSurface


culture chambers with the ability to stimulate your cultures with cyclic mechanical stretch. Versatile software enables programming of a wide array of stretch protocols for tremendous investigative flexibility.


NanoSurface culture chambers: biomimetic aligned nanoscale surface topography Nanotopography orientation: either parallel or perpendicular to applied stretch Chamber culture area: 2500 mm2


, 144 mm2 Applications


NanoSurface's Cytostretcher family of instruments stretch flexible cell culture chambers to provide cyclic mechanical strain to cultured cells.


Use the Cytostretcher to stretch cells on the bench-top or in a cell culture incubator.


Use the Cytostretcher-LV to perform stretching experiments on an optical microscope. It features a small footprint and self-contained design without bulky external controllers.


Elastomeric cell culture chambers are available in several sizes. Use standard chambers with unpatterned "flat" surface topography, or NanoSurface chambers, with biomimetic nanoscale surface topography.


The underlying matrix of the native myocardium has an aligned architecture (scale bar 10µm)


C2C12 skeletal myoblasts aligned on a NanoSurface Cytostretcher chamber by parallel nanotopography


, or 25 mm2


Cytostretcher


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