INF ECTION P R EVENTION


Yoshikawa K. (2004) DNA compaction by divalent cations: structural specificity revealed by the potentiality of designed quaternary diammonium salts. Chembiochem 5:360–386


10. Dyer DL et al. (1998) Testing a new alcohol-free hand sanitizer to combat infection. Association of peri Operative Registered Nurses Journal, 68:239- 251


11. Dancer SJ, White LF, Lamb J, Girvan EK, Robertson C. (2009) Measuring the effect of enhanced cleaning in a UK hospital: a prospective cross-over study. BMC Med. 8;7:28


12. Hayden MK, Bonten MJ, Blom DW, Lyle EA, van de Vijver DA, Weinstein RA. (2006) Reduction in acquisition of vancomycin-resistant enterococcus after enforcement of routine environmental cleaning measures. Clin Infect Dis.;42(11):1552–1560


13. WHO. WHO guidelines on hand hygiene in health care, World Health Organization, Geneva, Switzerland, 2009 edition.


14. CDC. Education Courses for Healthcare Providers on Hand Hygiene: Hand Hygiene, Glove Use, and Preventing Transmission of C. difficile (2017) — WD2703 and Hand Hygiene & Other Standard Precautions to Prevent Healthcare-Associated Infections. available at http://www.cdc.gov/ handhygiene/training.htm


15. DC. Core Elements of Hospital Antibiotic Stewardship Programs. 2017; available at http://www.cdc.gov/getsmart/healthcare/ implementation/coreelements.html


16. CDC. Guidelines for Environmental Infection Control in Health-Care Facilities Recommendations of CDC and the Healthcare Infection Control Practices Advisory Committee (HICPAC), 2019 at: https://www.cdc.gov/infectioncontrol/pdf/ guidelines/environmental-guidelines-P.pdf


17. Guh A, Carling P (2010) Environmental Evaluation Workgroup. Options for Evaluating Environmental Cleaning. Atlanta, GA: CDC


18. Merianos JJ. (2001) Surface-active agents. In: Block SS, ed. Disinfection, sterilization, and preservation. Philadelphia: Lippincott Williams & Wilkins, 283-320


19. Takasaki, A., Hashida, T., Fujiwara, S., Kato, K. and Nishihara, T. (1994a) Bactericidal action of a quaternary ammonium disinfectant, didecyldimethylammonium chloride, against Staphylococcus aureus. Japanese Journal of Toxicology and Environmental Health 40, 344±350.


20. Kramer A, Below H, Assadian O. (2012) Health risks of surface disinfection in households with special consideration on quaternary ammonium compounds (QACS). Bioaerosols - 6th International Scientific Conference on Bioaerosols, Fungi, Bacteria, Mycotoxins in Indoor and Outdoor Environments and Human Health; Albany, USA: Fungal Research Group Foundation


21. Tuladhar, E., de Koning, M. C., Fundeanu, I., Beumer, R., and Duizer, E. (2012) Residual Viral and Bacterial Contamination of Surfaces after Cleaning and Disinfection. Appl. Environ. Microbiol. 78, 2456– 2458, DOI: 10.1128/ AEM.07738-


22. Moore CB, Sayers N, Mosquera J, Slaven J, Denning DW. (2000) Antifungal drug resistance in


DECEMBER 2021


Aspergillus. J Infection 41: 203-220


23. Wessels S., Ingmer H. (2013) Modes of action of three disinfectant active substances: a review. Regul Toxicol Pharmacol. 67:456–467


24. Vieira D.B., Carmona-Ribeiro A.M. (2006) Cationic lipids and surfactants as antifungal agents: mode of action. J Antimicrob Chemother. 58:760–767


25. Tuladhar E., de Koning M.C., Fundeanu I., Beumer R., Duizer E. (2012) Different virucidal activities of hyperbranched quaternary ammonium coatings on poliovirus and influenza virus. Appl Environ Microbiol. 78:2456–2458


26. Tsao I.F., Wang H.Y., Shipman C., Jr. (1989) Interaction of infectious viral particles with a quaternary ammonium chloride (QAC) surface. Biotechnol Bioeng. 34:639–646


27. Pereira, B.; Tagkopoulos, I. (2019) Benzalkonium Chlorides: Uses, Regulatory Status, and Microbial Resistance. Appl. Environ. Microbiol. 85 (13), 1– 13


28. Shah, K.; Muriana, P.M.(2021) Efficacy of a Next Generation Quaternary Ammonium Chloride Sanitizer on Staphylococcus and Pseudomonas Biofilms and Practical Application in a Food Processing Environment. Appl. Microbiol. 1, 89–103


29. DeLeo, P., Huynh, C., Pattanayek, M., et al. (2020) Assessment of ecological hazards and environmental fate of disinfectant quaternary ammonium compounds, Ecotoxicology and Environmental Safety, 206. https://doi. org/10.1016/j.ecoenv.2020.111116


30. K. P. C. Minbiole, M. C. Jennings, L. E. Ator et al. (2016) From antimicrobial activity to mechanism of resistance: the multifaceted role of simple quaternary ammonium compounds in bacterial eradication, Tetrahedron, 72 (5): 3559–3566


31. Mayhall GC. (2004) Hospital Epidemiology and Infection Control, 3rd Ed. Chapter 85: Selection and Use of Disinfectants in Healthcare. Lippincott Williams & Wilkins. Philadelphia. p1505


32. Kramer, A., Schwebke, I. and Kampf, G. (2006) How long do nosocomial pathogens persist on inanimate surfaces? A systematic review. BMC Infect Dis 6, 130


33. Wylie, M., Craig, R., Gorman, S., McCoy, C.(2021) Development of a high-level light-activated disinfectant for hard surfaces and medical devices, International Journal of Antimicrobial Agents, 58 (1) https://doi.org/10.1016/j. ijantimicag.2021.106360


34. Cleveland JL, Robison VA, Panlilio AL. (2009) Tuberculosis epidemiology, diagnosis and infection control recommendations for dental settings: an update on the Centers for Disease Control and Prevention guidelines. J Am Dent Assoc 140: 1092−1099.


35. Centers for Disease Control and Prevention: Guidelines for Preventing the Transmission of Mycobacterium tuberculosis in Health-Care Settings, 2005. MMWR 2005; 54(RR17): 1−141


36. European Centre for Disease Prevention and Control. Handbook on tuberculosis laboratory diagnostic methods in the European Union – Updated 2018. Stockholm: ECDC; 2018.


37. Hidron AI, Edwards JR, Patel J, et al. (2008) Antimicrobial-Resistant Pathogens Associated With Healthcare-Associated Infections: Annual


Summary of Data Reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2006-2007. Infect Control Hosp Epidemiol 29:996-101


38. Gilbert P, McBain AJ. (2003) Potential impact of increased use of biocides in consumer products on prevalence of antibiotic resistance. Clin Microbiol Rev 16:189–208


39. McBain A.J., Rickard A.H., Gilbert P. (2002) Possible implications of biocide accumulation in the environment on the prevalence of bacterial antibiotic resistance. J Ind Microbiol Biotechnol. 29:326–330


40. Saccucci, M., Bruni, E., Uccelletti, D., et al (2018) Surface Disinfections: Present and Future, Journal of Nanomaterials, https://doi. org/10.1155/2018/8950143


41. Rutala WA, Cole EC. (1984) Antiseptics and disinfectants--safe and effective? Infect. Control 5:215-8.


42. MacDougall KD, Morris C. (2006) Optimizing disinfectant application in healthcare facilities. Infect Control Today 62-7


43. Sullivan, L., Boyce, J., Brown, A. et al. (2015) Quaternary ammonium compounds (QAC) issues encountered in an environmental services (EVS) department. Antimicrob Resist Infect Control 4, P42


44. Shere L. (1948) Some comparisons of the disinfecting properties of hypochlorites and quaternary ammonium compounds. Milk Plant Monthly March 1948:66-9.


45. Ganidi N.; Tyrrel S.; Cartmell E. (2009) Anaerobic Digestion Foaming Causes – A Review. Bioresour. Technol. 100 (23), 5546–5554


About the author


Dr. Tim Sandle is a pharmaceutical microbiologist, science writer and journalist. He is also a tutor with the School of Pharmacy and Pharmaceutical Sciences, University of Manchester for the university’s pharmaceutical micro- biology MSc course, and he lectures on sterile products at University College London. Dr. Sandle has served on several national and international committees relating to pharmaceutical microbiology and cleanroom contamination control (including the ISO cleanroom standards and the National Blood Service advisory cleaning and disinfection committee).


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