CONTINUING EDUCATION TEST The rise of molecular diagnostics for common maternal and fetal tests


MAY 2022 [This form may be photocopied. It is no longer valid for CEUs after November 30, 2023.] Passing scores of 70 percent or higher are eligible for 1 contact hour of P.A.C.E. credit.


TEST QUESTIONS Circles must be filled in, or test will not be graded. Shade circles like this:


1. Obstetricians and their clinical laboratory partners are increasingly focused on the identification of ________________commonly passed on to the developing fetus during gestation or to the infant during birth.


{viral and bacterial pathogens {rubella {West Nile virus {Colored blindness


2. Screening for primary CMV infection or reactivation during pregnancy or for CMV in newborns is currently included in universal screening recommendations.


{True


{Ultrasound {Environmental {Microbial {Molecular


4. What type of system includes instruments that handle everything from sample preparation and pre-analytics to analysis and reporting results?


{Sample-to-answer system {All-in-One system {Prep-to-Report system {Direct-Diagnostics system


5. What is the benefit of streamlined systems for small clinical laboratories?


{Because of these systems, they are exempt from women’s health testing


{They make it easier to expand their test menus and introduce women’s health


{They are able to charge higher fees if they conduct women’s health tests


testing {None of the above


6. Culture-based testing has been considered the gold standard for diagnosing most infectious diseases. Why?


{It’s inexpensive {It does not require advanced training


{All of the above


{It has the advantage of being familiar to pathologists and laboratorians worldwide


{False


3. What type of detection of HSV1, HSV2, and GBS has produced reliable results with high sensitivity and faster turnaround times?


Not like this:


7. Culture-based tests generally give reliable results, but what is their one weakness?


{Possible contamination {Readability {Testing limitations {Timing not in pace with healthcare needs


8. Newer diagnostics tests detect and quantify the nucleic acids present in a sample, allowing for diagnosis of known — and sometimes even novel — pathogens based on their DNA or RNA signatures.


{True


{viral infections {bacterial infections {fungal infections {parasitic infections


10. The conserved DNA or RNA genomic targets or signatures of multiple pathogens can be combined in a panel test, allowing laboratorians to test for several of the most common culprits in a single assay. When is this helpful?


{When labs are short-handed, and testing is back logged


{When symptoms of infection overlap, such as testing respiratory infections or


{During COVID-19 pandemic gastrointestinal infections


{Whenever working with DNA and RNA genomics


11. How is HSV1, primarily transmitted?


{Through blood transfusions {Through saliva {Through open cuts {Through unsanitary restrooms


12. According to estimates from the World Health Organization, _____ of adults under the age of 50 have acquired HSV1.


{34% {59%


{HSV1 {HSV2


{78% {67%


13. Which type(s) of HSV lead to lifelong infections where, in many cases, people are asymptomatic and never realize they have the virus?


{Neither {Both


{False


9. Molecular diagnostics have become the recommended laboratory method to aid in diagnosis of _________.


14. In developing babies, exposure to either type of HSV could lead to __________.


{Low birth weight {central nervous system infection {breathing difficulties {jaundice


15. How can HSV be passed by the mother to the infant?


{during birth {after birth {A and B {None of the above


16. Culture-based testing for these viruses typically takes a minimum of two to three days, while commercially available molecular diagnostic tests can generate highly accurate results in _________.


{60 minutes {24 hours


{30 minutes {18 hours


17. What can doctors do when they know that a mother had evidence of an active HSV infection while giving birth?


{immediately quarantine the mother {immediately quarantine the newborn {immediately test the mother {immediately test the newborn


18. Among newborns, infection by Group B Streptococcus is one of the leading causes of________________, making it a serious concern for neonatal care.


{blindness {meningitis and sepsis {pneumonia and strep {ear, nose, and throat infections


19. About 90% of babies born with congenital CMV infection will appear healthy at birth, but what percentage of these babies may die due to complications from the infection?


{20% {4%


{hearing loss {developmental delays {weakness in limbs {A and B


Tests can be taken online or by mail. Easy registration and payment options are available through NIU by following the links found at www.mlo-online.com/ce. PLEASE PRINT CLEARLY NAME CITY PHONE STATE ZIP MAILING ADDRESS INSTITUTION/FACILITY E-MAIL ADDRESS


Send your $20 check payable to Northern Illinois University with this form to: University Outreach Services, Northern Illinois University, DeKalb, IL 60115-2860 Phone: 815-753-0031 FEE NOT REFUNDABLE OR TRANSFERABLE


P = Poor; E = Excellent


1. To what extent did the article focus on or clarify the objectives?


P E


2. To what extent was the article well-organized and readable?


P E


3. How will you use the CE units? state license


recertification


employment other


CE Licensure Information for FL and CA:


FL: Your FL license number:____________________ (required for CE credit)


CA: Accrediting Agency: 0001 (for use in submitting your CE credits to CA)


MLO and Northern Illinois University (NIU), DeKalb, IL, are co-sponsors in offering continuing education units (CEUs) for this issue’s CE article. CEUs or contact hours are granted by the College of Health and Human Sciences at Northern Illinois University, which has been approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E.®


program. Approval as a provider of continuing education programs has been granted by the


state of Florida (Provider No. JP0000496). Continuing education credits awarded for successful completion of this test are acceptable for the ASCP Board of Registry Continuing Competence Recognition Program. Readers who pass the test successfully (scoring 70% or higher) will receive a certificate for 1 contact hour of P.A.C.E.® credit. Participants should allow three to five weeks for receipt of certificate. The fee for this continuing education test is $20. This test was prepared by Amanda Voelker, MPH, MT(ASCP), MLS, Clinical Education Coordinator, School of Health Studies, Northern Illinois University, DeKalb, IL


14 MAY 2022 MLO-ONLINE.COM HOME WORK


{43% {62%


20. Treatment with antiviral medications can potentially decrease the severity of long- term impacts of CMV, in infants, such as ______________.


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