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EDITOR Tom Mulligan, MSc Tel: +44 1403 220755 Email: tom@avakado.eu


SALES DIRECTOR Jaymin Amin, BEng Tel: +44 1403 220754 Email: jaymin@avakado.eu


PUBLISHER Mark Harrington, BSc Tel: +44 1403 220753 Email: mark@avakado.eu


PUBLISHING CONSULTANT Brian Cooper, MA, CEng


CHINA OFFICE Beijing Oriental Foreland Consultants Co, Ltd Tel: +86 10 84823421 Fax: +86 10 84846103 Email: info@fair114.com Contact: Steve Qiao


SUBSCRIPTIONS Tel: +44 1403 220760


WEBSITE DESIGN Siric Communications Tel: +44 1306 747052 Email: info@siric.com


WEBSITE www.avakado.eu/dev/sp2-Magazine/Home


ANNUALSUBSCRIPTION £95.00 UK, £125.00 (US$250.00 or €185.00) overseas (includes postage) sp2


is published seven times a year:


January/February, March/April, May/June, July/August, September, October, November/December by avakado media.


Published by avakado media, Global House, 13 Market Square, Horsham, West Sussex RH12 1EU. UK, Tel: +44 1403 220760 Fax: +44 1403 220761


Printed in England by Manor Creative, Eastbourne, East Sussex, UK ©avakado media, 2011 ISSN 1476-184X


ABC Membership application approved


In this issue:


Venoms as sources of peptide drugs Antibody optimisation technology Globalisation of contract research Biocatalysis in drug discovery


discovery , development, delivery for pharma & biotech


November/December 2011 www.avakado.eu


CONTENTS EDITOR’S PAGE NEWS


PEPTIDES & PROTEINS BIOLOGICS


New investments in peptide technology and manufacturing Identification and synthesis of complex peptide therapeutics


23


Accelerating antibody optimisation and therapeutic development APIs


26


Contract manufacturers look to APIs for business opportunities PHARMACEUTICALS


28


Combining small molecules, viruses and polymers for new drugs CONTRACT RESEARCH


30


Contract research and bioinformatics: a global perspective DRUG DISCOVERY


An unusual technologymarriage to assist in drug discovery FORMULATION & DELIVERY


PLUS: The Life Science CLUSTERSSupplement is published in the centre of this issue


32 35


4 6


16


The avakado media team wishes all our advertisers and readers a Merry Christmas and best wishes for the New Year Cover picture:


iStockphoto.com © Igor Djurovic November/December 2011 sp2 3


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