PEER-REVIEW | BODY CONTOURING | CELLULITEIS IT A FAT PROBLEM?


Gustavo Leibaschoff reviews the pathology, evaluation, and available treatments for cellulite, including platelet rich plasma and dietary supplementation


ABSTRACT Cellulite (edematous fibro- sclerotic panniculopathy) or


FEF (female evolutive


fibroedema) represents an aesthetic pathology that requires a precise therapeutic strategy characterised by an integrated treatment with a variety methodologies. Cellulite is a very common


condition in women in whom the skin acquires an orange peel


or mattress appearance


and is the result of a number of biochemical and metabolic changes. The presence of cellulite is a significant source of patient dissatisfaction. According to the most recent studies, those changes start in the ECM extracellular matrix.


medical equipment, and pills. However, the importance of this purely aesthetic problem should not be underrated. Beauty plays an important role in human relationships in a social setting1 Koblenzer2


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GUSTAVO LEIBASCHOFF is President of ICAM USA Inc; International Consultant in Aesthetic Medicine; President of the International Union of Lipoplasty; Director of the International Academy of Cosmetic Gynecology; Member of the American Academy of Cosmetic Surgery; and Director of the International School of Carboxitherapy


email: drghl@icam-usa.com 38 ❚


KEYWORDS cellulite, platelet rich plasma, PRP, adipose tissue


. mentions a number of studies that demonstrate real


benefits from maintaining an appearance of youthfulness and beauty during all stages of life. When these patients stare in the mirror and see their cellulite, they experience diverse negative feelings, like anger, guilt, sadness, impotency, shame, discomfort, and the desire to cover themselves. Cellulite is an actual pathology, something uncomfortable and unaesthetic, which results in a disease for the patient. Our duty as physicians is to suggest the best scientific methods to repair tissue damage and pathological disorders.


Definition There was a time when cellulite was conceived as a mere increase of subcutaneous


fat in tissues


associated with an altered lymphatic and venous flow and lymphatic stasis. Furthermore, there was a deeply- rooted notion that cellulite was closely related with the specific stasis subsequent to


January/February 2015 | prime-journal.com


The physiopathology shows modification of the connective tissue


and the extracellular


matrix; a decrease in the microcirculatory (the network of diminutive arteries and veins) and lymphatic system, resulting in an interstitial oedema and microangiopathy due to stasis representing triggering factors that also support the


pathological process. In the end hyperplasia and hypertrophy of the fat tissue with a sclera connective evolution occurred (skin retractions). The ECM is a three dimensional complex of proteins, carbohydrates, salts, fixed cells, migrating cells and fibres. An effective cellulite treatment should correct first the changes occurred in the


extra cellular matrix, only way to achieve improvement in cellulite condition. The


treatment of


cellulite should follow different steps. The goal is to correct the physiopathology, all the changes produced in the ECM, connective tissue, microcirculation and adipose tissue.


ELLULITE IS CERTAINLY NOT A SERIOUS CONDITION from the medical point of view but it does represent the most widely spread and least tolerated aesthetic complaint for women. The condition is well known due to intense publicity campaigns in the media as the cosmetics industry promotes its creams, electro-


Cellulite is an


actual pathology, something


uncomfortable and unaesthetic,


which results in a disease for the patient.


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