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Moderate to Severe Rheumatoid ArthritisRA


Can you grasp this?


Fasten this? Oh, yes I can!


Still fi nding it tough to do everyday things?


ORENCIA may help.


• Relieve the pain, swelling, and fatigue of RA • Control the advance of joint damage • Help improve physical and emotional health-related quality of life


ORENCIA has been proven to make a difference for many patients, including those who haven’t been getting enough help from treatments such as methotrexate, Enbrel®, Humira®, and Remicade®. There are several treatment options for RA. Ask your rheumatologist if ORENCIA is right for you.


Find out more about ORENCIA Call: 1-800-ORENCIA Visit: www.ORENCIA.com Important Safety Information about ORENCIA:


Before you receive ORENCIA, tell your doctor if you: • are prone to or have any infection like an open sore or the fl u because an infection could put you at risk for serious side effects from ORENCIA. Call your doctor right away if you have a fever, feel very tired, cough, feel fl u-like, or have warm, red, or painful skin.


• have a history of a chronic lung disease called COPD because you may get certain respiratory problems more often with ORENCIA such as worsened COPD, pneumonia, cough, or trouble breathing.


• have diabetes and are using a blood glucose monitor. Some monitors can give falsely high readings with ORENCIA on the day of your infusion.


• are nursing, pregnant, or planning to become pregnant. Talk with your doctor about whether to continue with ORENCIA.


Please read the Important Facts on the following page.


© 2008 Bristol-Myers Squibb Company


• take any other medicines, especially other biologics for RA such as Enbrel®


, Remicade® , Humira® , or Kineret® . Taking


ORENCIA with biologics for RA may increase your chance of getting a serious infection.


ORENCIA can cause serious side effects including serious infections and allergic reactions. Also, certain kinds of cancers have been reported in patients receiving ORENCIA. It is not known if ORENCIA increases your chance of getting certain kinds of cancer. You should not receive ORENCIA with certain vaccines. ORENCIA may cause some vaccines to be less effective. Common side effects include headache, upper respiratory tract infection, sore throat, and nausea.


ORENCIA is a 30-minute IV infusion given by a healthcare professional, every 4 weeks after initial dosing regimen. If you have any questions about ORENCIA, talk with your doctor.


™


ORENCIA is an RA treatment that works differently. It’s a prescription medication used to treat adults with moderate to severe RA and has been shown to:


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.


427US08AB28923 Oct/08 ORENCIA is a registered trademark of Bristol-Myers Squibb Company. All other trademarks are property of their respective companies.

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