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News Update presents up-to-date wound care news, including the latest from associations, clinicians and industry. If you have a news item for the next edition, please email the editor at: scalne@woundsinternational.com


Peptides can decrease the incidence of flap necrosis


Research published inWounds has shown that the incident of flap necrosis can be significantly decreased with the peptides, adrenomedullin (ADM) and glucagon-like peptide-1 (GLP-1). Researchers cut a cutaneous flap measuring 8 x 3cm in the


Image: Rat Credit: jepoirier on Flickr.


abdomens of rats and treated four different groups. The control group was treated with saline and the other three groups were treated with different doses of ADM and GLP-1. All three groups that were treated with peptides had an increase of blood flow to their wound flaps, decreasing necrosis when applied to the superficial inferior epigastric artery. Blood flow was shown to reach all areas of the flaps with the same statistical evidence for all doses. Click here for more info.


Device brings comfort to patients with skin damage


Wounds International has launched a 12-page review document, which describes the mode of action of the Skin IQ™ Microclimate Manager (MCM),


demonstrating its use in a range of case studies. The Skin IQ™ MCM is a coverlet with


a small negative airflow device, which pulls moisture and heat away from the patient. When used in conjunction with a pressure redistribution mattress, the Skin IQ™ MCM enables control of the microclimate at the interface between the skin and the support surface. This has potential benefits for patients


Monitoring wound fluid can indicate ‘With respect to diagnostic


wound severity A recent study has found that measuring the amount of uric acid present in wound fluid can help to distinguish the wound’s severity. Uric acid plays a part in inhibiting wound healing as it deposits monosodium urate crystals into the wound, which creates an inflammatory response. By measuring the components of wound fluid, researchers found that when the level of uric acid is high, the wound is more severe and long lasting.


applications, the severity of a wound could be monitored by detecting the levels of uric acid or the levels of one or more of the uric acid precursors in wound fluid,’ the researchers explained. ‘Monitoring changes of purine metabolites in wound fluid is therefore likely to provide valuable information regarding the healing patterns of chronic venous leg ulcers.’ Click here for more info.


with many different skin diseases and for those at risk of, or suffering with, moisture lesions and pressure ulcers. Professor Mike Clark, Nils Lahman and


Joyce Black are the main contributors to the document, with support from those working in areas such as intensive care and oncology. In addition, Jackie Denyer, clinical nurse specialist from Great Ormond Street Hospital in the UK, describes its use in a patient with epidermolysis bullosa. She writes that ‘the patient was constantly damp from sweat and the wounds on her feet, and reported immediate comfort from the Skin IQ microclimate manager’. The case studies demonstrate how


the device offers relief and early results indicate improved outcomes. Click here for more info.


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Wounds International Vol 3 | Issue 1 | ©Wounds International 2012


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