News from the UK...
Registration of a Low Uric Acid Dalmatian Import from the USA *
At its meeting on 5th January 2010, the Kennel
Some years ago in the USA, a cross-breeding was
Club General Committee accepted an application
carried out between a Dalmatian and a Pointer
to register an imported Dalmatian produced from
with the intention of producing offspring that were
a breeding programme which was originated
low uric acid (LUA) excretors, because the Pointer
with an intentional Pointer/Dalmatian cross. This
used in the cross would not have carried the mu-
cross-breeding was carried out in the USA as part
tant gene. The offspring from this mating and their
of a programme aimed at introducing the low (or
descendants have subsequently been back-crossed
normal) uric acid gene into the Dalmatian breed.
with purebred Dalmatians over many successive
generations.
This decision is subject to certain conditions,
which include the dog being examined by two
Decision
Championship Show judges to confirm that its
external appearance and characteristics are repre-
Recently, the Kennel Club received a proposal to
sentative of the breed.
register an imported LUA Dalmatian that is de-
scended from the initial Pointer/Dalmatian cross.
The decision taken by the General Committee
The outcross Pointer appears at least 13 genera-
is in line with the Kennel Club’s commitment to
tions back in the pedigree of the imported dog.
consider applications to register dogs from out-
In line with the general aim of the KC to help
crossings and inter-variety matings if it is felt that
individual breeders and breed clubs to improve
to do so may present potential health and welfare
the health and welfare of future litters, the General
benefits.
Committee has agreed to register this imported
LUA Dalmatian subject to confirmation from two
The Kennel Club consulted the Dalmatian breed
championship Show judges that the imported dog’s
clubs on this matter and their joint feedback was
external appearance and characteristics are repre-
considered at length by the General Committee
sentative of the breed.
before arriving at this decision.
The registration records of this dog and its descen-
Background
dants will be annotated by the KC’s normal aster-
isk system whereby the progeny of the first mating
It is believed that the Dalmatian breed is fixed
between the dog and a registered Dalmatian, the
for a recessive mutation of a gene that alters uric
F1 progeny, will have their registrations annotated
acid metabolism, resulting in increased urinary
with three asterisks. Then, when F1 progeny are
excretion of uric acid. This gene is not expressed
bred from, their progeny, the F2 progeny, will be
in most other breeds of dog which excrete lower
annotated with two asterisks. F2 progeny will pro-
amounts of uric acid in their urine.
duce F3 progeny which will be registered with one
asterisk. The F4 and subsequent generations will
The use of a recently developed DNA test for this
have no special annotation.
genetic mutation on Dalmatians in the USA has
shown that the frequency of the normal gene is
In addition to the above conditions the committee
close to zero in the USA population of the breed.
also agreed that the registrations of all progeny
Similar DNA testing of the UK population has
would be endorsed with the restriction ‘Not eli-
yet to be undertaken, but it is likely that a com-
gible for Export Pedigree’ for the next five years,
parable scenario exists in the UK population of
and the owners would be required to submit a
Dalmatians.
health report, to include BAER testing results, on
all progeny in five years’ time.
* Posted on Jan 12, 2010 on The Kennel Club Website:
http://www.thekennelclub.org.uk/
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