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rate, hens’ body weight and egg qualities (shell and albumen). In the first trial(2)


The third trial(2) , positive control corn-based diets have been


compared to a negative control diet formulated with -3 % AME and dAA, with or without Rovabio®


Advance. As expected, the negative


control diet resulted in a significant increase in the feed conversion rate (+4.5%), while the addition of Rovabio®


Advance had a highly significant


positive effect (P<0.001) leading to the same feed conversion rate as the positive control diet (Figure 1).


Figure 1: Laying trials proving the potential of Rovabio® to save 3% AME and dAA


Advance


compared wheat-based diets using a positive


control and a negative control with -3 % of AME and dAA. As in the other trials, the negative control diets showed lower performance (P<0.05) as compared to the positive control, and Rovabio®


for recovery of all losses: FCR, egg weight, and egg mass. UNIQUE BENEFITS OF ROVABIO®


ADVANCE Rovabio® Advance is now authorized in most parts of the world and


is available in different forms (powder at 50 g/MT of feed or liquid at 100 to 200 mL/MT) to fit various feed mill applications. “With this new registration, Rovabio®


Advance confirms its leading position as the only


feedase for unmatched profitability in feed and poultry production,” says Adrien Rivayrand, Enzyme Product Manager for Europe, Africa and the Middle East. With a potential to replace 3% of the AME and dAA, Adisseo offers the possibility of decreasing feed costs by up to 12 €/ MT of feed treated with Rovabio®


100,000 MT of poultry feed per year, Rovabio®


Advance. In a feed mill producing Advance could generate


an extra margin of at least 300,000 € per year compared to former generations of NSP enzymes.


The results are confirmed in a second trial(3) , with a control diet


reduced by 65 kcal/kg of metabolizable energy and -4 % of dAA. The addition of Rovabio®


of performance observed with the negative control diet (Figure 1). Advance allowed the recovery of the significant loss


(1) CERN, Center of Expertise and Research in Nutrition, Commentry, France


(2) Zootest, France (3) Universidad Nacional Autónoma do México (UNAM), Mexico Advance allowed


Guanidinoacetic acid in pigs By Holly Malins, Evonik Nutrition & Care GmbH


For decades now, athletes have been able to naturally enhance their sporting performance through the addition of creatine monohydrate to their nutritional programme. Creatine plays a vital role in cellular energy metabolism and essentially functions as a back up to the


Figure 1: Biochemical pathway of creatine


ATP system in order to store and mobilize energy when required on a short notice, particularly in muscle cells (Michiels et al., 2012). Traditionally considered as a semi-essential nutrient, creatine is normally synthesized by animals in the liver and kidneys mainly from glycine and arginine through a methylation process (Figure 1). It is however likely that the capacity for endogenous synthesis is limiting in high yield farming animals (Mousavi et al., 2013) and thus, creatine must be provided as a dietary source to meet the genetic potential for those high-yielding farm animals.


CREATINE SOURCES IN FEED Due to the restrictions of feeding animal by-products in the European Union, vegetarian diets have no natural source of creatine and even fishmeal only contains approximately 1.1% creatine. Research has shown that pigs fed supplemental creatine monohydrate had a higher average daily gain (Maddock et al., 2000; O’Quinn et al., 2000), however due to the thermal instability of creatine monohydrate


PAGE 46 MAY/JUNE 2017 FEED COMPOUNDER


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