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Alcohol can play a useful role in relieving anxiety and potentiating the action of many lethal drugs. As a pre-medication it should be taken carefully so that judgement is not impaired. This is particularly important when there are several steps involved such as starting the gas flow and positioning an Exit bag. Note also that alcohol can sometimes be totally counter- productive. Alcohol can limit the effectiveness of an anti-emetic and, instead of preventing vomiting, it can provoke it.
Alcohol can also be useful as a post-medication where spirits or a liqueur can be taken to remove the aftertaste of a lethal barbiturate like Nembutal. The respiratory depressing action of the alcohol, and its rapid action, can usefully potentiate lethal hypoxic hypoxia drugs such as morphine and other opiates, the barbiturates, chloral hydrate etc. The amount of alcohol taken is dependent on personal sensitivity and experience. Use with care. .
Cannabis is a useful pre-medicating sedative while serving the dual function of acting as an anti-emetic. Cannabis can be taken 15 - 20 minutes prior to the lethal drug, either by smoking or vaping. Oral consumption can be slow and often unpredictable and for these reasons should be avoided. Dose will be determined by personal history and experience.