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While Chloroquine phosphate (marketed as Avlochlor 250mg tablets) had been readily-available for many years in many countries over-the-counter, it was unknown that chloroquine phosphate was available on websites such as eBay as a fish tank additive. Chloroquine phosphate remains a useful end of life method (See the Chapter on ‘Chloroquine’).
Pre-COVID, the Exit RPA rating for chloroquine (as an end of life option) was 76% which is a little lower than sodium nitrite. Chloroquine availability was then rated at 10/10. The availability rating post-COVID has now dropped to an estimate of ~ 4/10. This gives chloroquine a new rating of a low 60%.
Barbiturates The implementation of ongoing, international travel restrictions and the closure of many international borders has meant that physical travel to purchase over-the-counter veterinary Nembutal is a difficult option. This is in stark contrast to pre- COVID times when Nembutal could be reliably sourced without a script in a number of South American countries. While the drug may still be available, it is the inability to travel that severely limits this as an option.
That said, Nembutal remains available over the Internet, although it is an illegal purchase.
Nitrogen & Gas Techniques The need for ventilators and the potential use of CPAP and BiPAP machines as passive ventilation devices has drawn new attention to these machines and to their use of sealing, ‘sleep friendly’, positive air pressure delivery systems. This has highlighted their possible future use as positive-pressure, end of life methods (if an external source of a gas such as nitrogen is used).