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PPi Editor


Brian Nation CSci FIBMS briannation@stepcomms.com


Publisher Geoff King geoffking@stepcomms.com


Journal Administration Katy Cockle


katycockle@stepcomms.com


Advertisement Sales sales@pathologyinpractice.com


Design Dave Woodall


Publishing Director Trevor Moon


trevormoon@stepcomms.com


Advisory Panel Dr Nigel Brown FIBMS Gavin Knight CSci FIBMS Wendy Leversuch CSci FIBMS Dr Suzy Lishman CBE FRCPath Dr Stephen MacDonald FRCPath Prof Gerry McKenna DSc CSci FIBMS Malcolm Needs CSci FIBMS Dr Sarah Pitt CSci FIBMS Dr John Rees FIBMS


Pathology in Practice may not be reproduced in any way without prior written consent of the publisher.


Method comparison studies, see page 15 OPINION


One Health: current and future challenges ARTICLES


Method comparison studies: an introduction to acceptability criteria


Biomedical laboratory science: introducing an international perspective


Plasma viscosity: accuracy, precision and suitability – who wants it?


Releasing pressure on pathology services: RFID technology holds the key


Reducing the COVID-19 burden: diagnostic tests and the patient pathway


Point-of-care testing aids decision-making in a GP-based assessment hub


Advances in liver research, see page 44


Innovative haemostasis systems: a solution for routine and special testing


Advances in hepatology: researching cirrhosis, HBV and intestinal microflora


Pathology partnership strengthened during SARS-CoV-2 pandemic


Step House, North Farm Road Tunbridge Wells, Kent TN2 3DR Tel: 01892 779999 Fax: 01892 616177


Email: info@pathologyinpractice.com


ISSN 1465-9131 Printed by CPI Colour


Integrated pathology services, see page 50


Hepatitis B virus: a small selection of research interest in the current literature


Rapid triaging of patients during COVID-19 59 COVER STORY


Triaging patients presenting with acute respiratory infection symptoms in the influenza season can be a minefield, without the added pressure of a global pandemic. Identifying which patients have a virus and which are suffering from a bacterial infection can inform treatment decisions and have a direct impact on the spread of viral infection and antimicrobial resistance.


Dr Helen Dillon, Consultant in Infectious Diseases at South Warwickshire NHS Foundation Trust, stated, “At Warwick Hospital we initially used FebriDx to assist in ‘stepping down’ patients who were negative for SARS-CoV-2 by PCR tests, but had ongoing clinical suspicion of COVID-19. This enabled us to free our COVID beds much more quickly and reduced the need to open additional beds. We are now also using FebriDx as part of our front door triage process. “Using FebriDx at the point of admission has allowed us to stream patients quickly and


efficiently to the most appropriate areas. This has had a huge impact in maintaining flow through the hospital as well as maintaining safety for patients and staff.”


T: +44 (0)1782 575180 E: enquiries@unahealth.co.uk W: www.unahealth.co.uk WWW.PATHOLOGYINPRACTICE.COM DECEMBER 2020 3


Barrett’s metaplasia in the upper GI tract: subtyping, stem cells and receptors


Diagnostic testing in cases of SARS-CoV-2 adverse outcomes


13


CONTENTS


Volume 21 Issue 6 December 2020


www.pathologyinpractice.com NEWS 5


15 20 23 28 31 36 39 44 50 52 56


PATHOLOGY IN PRACTICE


Page 1  |  Page 2  |  Page 3  |  Page 4  |  Page 5  |  Page 6  |  Page 7  |  Page 8  |  Page 9  |  Page 10  |  Page 11  |  Page 12  |  Page 13  |  Page 14  |  Page 15  |  Page 16  |  Page 17  |  Page 18  |  Page 19  |  Page 20  |  Page 21  |  Page 22  |  Page 23  |  Page 24  |  Page 25  |  Page 26  |  Page 27  |  Page 28  |  Page 29  |  Page 30  |  Page 31  |  Page 32  |  Page 33  |  Page 34  |  Page 35  |  Page 36  |  Page 37  |  Page 38  |  Page 39  |  Page 40  |  Page 41  |  Page 42  |  Page 43  |  Page 44  |  Page 45  |  Page 46  |  Page 47  |  Page 48  |  Page 49  |  Page 50  |  Page 51  |  Page 52  |  Page 53  |  Page 54  |  Page 55  |  Page 56  |  Page 57  |  Page 58  |  Page 59  |  Page 60  |  Page 61  |  Page 62