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A & B5Hematoxylin and eosin stain of normal colon (A) and IBD (B), x200.
C & DUsing wet tissue for SEM: (C) “en face” SEM photograph of normal colon; (D) “en face” SEM photographs of colon affected by Crohns Disease show marked irregularity of the cell borders with elongation of the crypts’ orifices, x3200.