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Binding Site


Binding Site is a Specialist Protein company committed to the research, development, manufacture and distribution of innovative immunodiagnostic assays for the global laboratory market. With extensive expertise in antibody specificity technology, Binding Site gives clinicians and laboratory staff the tools to significantly improve diagnosis and management of patients across a range of cancers and immune system disorders.


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The headquarters of The Binding Site Group Ltd is located in Birmingham, UK and employs over 500 people.


In addition to research activities, the main site houses product development and manufacturing along with global distribution, marketing and administrative functions. Direct sales and product support to customers in the UK are based here together with sales and technical support provided to our distributor network in over 80 countries .


Direct Binding Site sales and support organisations are also based in:


San Diego, California for USA & Canada Schwetzingen, near Heidelberg for Germany, Austria & Switzerland


Grenoble for France & French speaking distributor markets Barcelona for Spain & Portugal


Prague for Czech Republic & Slovak Republic Antwerp for Belgium, Netherlands & Luxembourg Bergamo, near Milan for Italy São Paulo for Latin America


is a well established assay used for the diagnosis and monitoring of Multiple Myeloma, a cancer of cells in the bone marrow. Freelite comprises two immunodiagnostic assays for accurate and rapid quantification of free  (kappa) and free  (lambda) immunoglobulin light chain concentrations. These assays can be performed on a significant number of automated platforms giving a sensitivity, accessibility and consistency never achievable before. Freelite has allowed significant improvements in both laboratory and clinical practice for the detection, prognosis and monitoring of B cell malignancies.


Innovative Immunodiagnostic Assays from Binding Site Freelite®


Hevylite®


is a unique immunoassay panel designed for identification and quantification of immunoglobulin heavy and light chain isotypes. These kits are available on the SPAPLUS®


and BNTM II


analysers. Like Freelite, Hevylite is used in monitoring patients with Multiple Myeloma and other monoclonal gammopathies.


Freelite and Hevylite together provide the best monitoring solution for the management of Multiple Myeloma patients.


 Diseases. Binding Site is a market leader in the development of products for the investigation of immune status including PID. Our current range of specialised products includes assays for: • Measuring specific antibody response to vaccination • Quantifying immunoglobulins & subclasses • Measuring complement proteins


Optimised Instrumentation and Assays We are delighted to introduce Optilite®


; the latest member of our


analyser family. With its custom design and powerful technology Optilite delivers the ideal solution for your special protein laboratory. Optilite joins our existing Specialist Protein Analyser, the SPAPLUS®


. Both systems have been developed exclusively for Binding Site Specialist Protein Assays, bringing harmony to assay and analyser alike. These dedicated systems, along with Binding Site’s exceptional support, ensure optimal assay performance, system throughput and user experience.


Reducing our Impact on the Environment Quality Assurance


Our manufacturing site has quality systems approved to both ISO9001 and ISO13485:2003 certification. These, together with strict adherence to rigorous internal quality control procedures, ensure customers can be confident in the quality of Binding Site products.


Assays for in vitro diagnostic use have been FDA cleared for the USA and CE marked for Europe. Performance of our assays is regularly monitored by participation in a number of independent national and international quality assurance schemes.


Binding Site’s environmental policy outlines our commitment to limit the overall impact our processes have on the environment. The new 2011 head office was built with a focus on reduced energy and water consumption, has provisions for rainwater harvesting and meets strict carbon emission restrictions. All staff are trained on our Reduce, Reuse & Recycle policy.


Research


We also make available a range of antigens and antibodies which are for research use only. For further information on these products, please visit www.immunologicals.com


More information at: www.bindingsite.com

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