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Contents


Handbook Contents


Factor Xa 04 Factor Xa inhibition in anticoagulation Erik Holy and Jan Steffel


Clinical indications 07 Anticoagulation in atrial fibrillation Marco Alings


11 Anticoagulation in venous thromboembolism Thomas Vanassche and Peter Verhamme


Safety 16 Safety issues and limitations of long-term anticoagulation Michiel Coppens


NOACs 19 NOACs: an overview in AF A John Camm and Irena Savel


24 Patient management and monitoring Sylvia Haas


27 Focus on edoxaban Barbara Clark


Role of the pharmacist 31 Patient education and therapy optimisation Oweikumo Eradiri


Editor, Secondary Care Andrea Porter


Commissioning Editor Annabel De Coster


Art/Design Evelyn Bercott


Sales Manager, Secondary Care Jennifer Richardson


Managing Director Alex Beaumont


Copyright © Cogora Limited 2016. The contents of this publication are protected by copyright. All rights reserved. No part of this publication may be produced, stored in a retrieval system or transmitted in any form or by any means without the written permission of the publisher. The views expressed in this publication are not necessarily those of the publisher or editorial advisors. While the publisher and editorial advisors have taken every care with regard to accuracy of editorial and advertisement contributions, they cannot be held responsible for any errors or omissions contained therein. Published in the United Kingdom by Cogora Limited, 140 London Wall, London EC2Y 5DN, UK


Support for the development of this handbook was provided by Daiichi Sankyo Europe


T +44 (0)20 7214 0500 E hpe@cogora.com


F +44 (0)20 7214 0501 W www.cogora.com


2 www.hospitalpharmacyeurope.com


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