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Contents


Supplement Contents


Guidelines 02 Appropriate use of antifungal guidelines Matteo Bassetti and Elda Righi


Pharmacoeconomics 05 Pharmacoeconomics of echinocandins Lubos Drgona


Diagnostic versus empirical 08 Diagnostic-driven strategy versus empirical treatment: how to save costs? Fiona Dignan


Legislation 11 EC Directive on safety-engineered devices: safer for nurses and pharmacists? Debra Adams


Oral step down 15 Antifungal stewardship helps oral step down in haematology patients Craig Williams


Intensive care 18 The challenge of systemic Candida infections Markus Ruhnke and Agata Mikolajewska


PK/PD 22 Echinocandins: pharmacokinetics and pharmacodynamics Federico Pea


Editor, Secondary Care Andrea Porter


Features Editor Andrew McCulloch


Art Director Evelyn Bercott


Head of Business Development Neil Morris


Managing Director Alex Beaumont


Copyright © Cogora Limited 2014. The contents of this publication are protected by copyright. All rights reserved. No part of this publication may be produced, stored in a retrieval system or transmitted in any form or by any means without the written permission of the publisher. The views expressed in this publication are not necessarily those of the publisher or editorial advisors. While the publisher and editorial advisors have taken every care with regard to accuracy of editorial and advertisement contributions, they cannot be held responsible for any errors or omissions contained therein. Published in the United Kingdom by Cogora Limited, 140, London Wall, London EC2Y 5DN, UK


Financial support for the development of this Handbook has been provided by Pfizer


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