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Child 12–14 (body weight >50kg), >15 years and adult: <40kg: 200mg BD first 24h then 100mg BD; >40kg: 400mg BD first 24h then 200mg BD. If response inadequate, increase MD to 150mg (<40kg) or 300mg (>40kg). Higher doses may be required to achieve therapeutic levels.
Adult: 4mL of 2% solution BD
• Unlicensed for this indication: In vitro activity against P. aeruginsa and B. cepacia complex has not been replicated in vivo, however, successful eradication of B. cepacia reported in a non-CF patient
• Perform test dose under supervision Route Additional prescribing information