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Child 1 month – 18 years: 10–15mg/kg BD (total daily dose may be given in 3 divided doses) Adults, up to 20mg/ kg/day; in two to three divided doses.
Route Additional prescribing information PO
• Doses may differ to manufacturers recommendations for other indications; not licensed for this indication • Recommended to start soon after diagnosis of CFLD is made; evaluate efficacy at 3–6 months after starting and adjust dose as necessary • The daily dose may be divided unequally, with the larger dose given in the evening to counteract overnight increases in biliary cholesterol concentration
Child and adults: Dosage should be adjusted according to individual requirements (max. 20 tablets per day in severe depletion in adults).