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Drugs which people with Brugada syndrome should avoid:


Below is a list of the drugs that people with Brugada syndrome should avoid. Please check with your pharmacist if your doctor prescribes any new drugs for you, as this list may not be complete.


Adapted from: Brugada syndrome. Napolitano C, Priori SG. Orphanet J Rare Dis. 2006 Sep 14;1:35. Brugada Syndrome: Report of the Second Consensus Conference Charles Antzelevitch et al. Circulation. 2005;111:659-670


Drug Group Class I antiarrhythmics:


Local anaesthetics (non antiarrhythmic): Alpha adrenergic agonists: Beta-blockers:


Calcium channel blockers: Nitrate:


Potassium channel activators: Parasympathetic agonists: Ergot alkaloids:


Tricyclic antidepressants:


Tetracyclic antidepressants: Phenothiazine:


Selective serotonin reuptake inhibitors: Opioid analgesics:


First-generation antihistamines: Others:


Drugs to be avoided


all to be avoided including flecainide, propafenone, disopyramide, pilsicainide, ajmaline, procainamide, cibenzoline bupivacaine


methoxamine, noradrenaline


all to be avoided especially propranolol verapamil, nifedipine, diltiazem isosorbide dinitrate, nitroglycerine pinacidil


acetylcholine ergonovine


all to be avoided including amitriptyline, nortriptyline, desipramine, clomipramine


maprotiline


perphenazine, cyamemazine fluoxetine


propoxyphene dimenhydrinate


propofol, lithium, cocaine, alcohol intoxication


Cardiac Risk in the Young


36


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