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Analysis Water Quality Monitoring and Human Health


for micrograms per liter. There are 1,000 micrograms in a milligram. Ug/l are the same as ppb or parts per billion. How much is a mg/l or ppm anyway? One ppm is equivalent to one drop of water diluted into 50 liters, which is about the fuel tank capacity of a compact car. A part per billion is equivalent to 1 drop of water diluted into 250 chemical drums filled with liquid. Although these are indeed small numbers, certain contaminants can be harmful to human health if they are present in the parts per trillion, or even present at all.


Toxicity


Would you rather consume a teaspoon or sugar or a teaspoon of dioxin with your morning coffee? Different chemical compounds have different degrees of toxicity. A teaspoon of sugar won’t do you much harm; a teaspoon of dioxin will! So, for example, look at the table below. Phosphorus and arsenic are both present at concentrations of 0.2 mg/l.


Chemical Amount (mg/L)


Phosphorous 0.2 Arsenic


0.2


In fact, both phosphorus and arsenic in this example are present at more than 20 times an acceptable level. However, arsenic is far more toxic than phosphorus and would pose a far greater human health risk. The relative toxicity of different chemical compounds is determined by a number called the LD50. The LD50 is the “lethal dose,” of the chemical that kills 50% of the lab animals exposed to it. This is a rough, not a perfect way, to compare toxicity of different chemicals. For example, in the table you can see how much salt it takes to kill 50% of the rats compared to how much arsenic, dioxin and other substances it takes.


Sugar Salt


Caffeine Nicotine Arsenic Dioxin


Chemical Means of exposure, Animal Oral, rat Oral, rat Oral, rat Oral, rat Oral, rat Oral, rat


LD50 (mg/kg)


29,700 3,000 192 50 13


0.02


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