arTIcle | PaTienT exPerience |
Safety and efficacy of a non-animal croSS-linked
examining the hyaluronic acid Marina Landau presents the results of a non‑randomised,
non‑interventional, multi‑centre study into the safety and efficacy of a range of hyaluronic acid fillers
ABSTRACT Objective: This study aimed to collect data about patients’ experiences of aesthetic improvements and the safety of the Princess® Filler for the correction of wrinkles.
Design: The study was a non-randomised, non-interventional, multi-centre study.
MARINA LANDAU, MD, is Dermatologist, Wolfson Medical Center, Holon, Israel.
And the ‘Princess Filler’ Investigation Group.
email:
mlandau@zahav.net.il
Results: A total of 71 patents (five males, 66 females) underwent intradermal injections for the facial enhancement of a number of regions of the
biodegradability, the simplicity of the treatment procedure, and the low pain levels associated with the injection process. Hyaluronic acid is a natural substance and a significant component of the
T
KEYWORDS hyaluronic acid, fillers, wrinkle, rejuvenation, BDDE, satisfaction assessment
42 ❚
extracellular matrix, where it plays a vital role in water homeostasis and wound healing2
. The hyaluronic acid molecules used in dermal fillers
are chemically cross-linked in order to improve consistency and increase the intradermal residence time of the filler. The range of hyaluronic acid fillers available on the market differ with regard to the source material (e.g. rooster combs or biofermentative origin from Streptococcus equi), concentration, method and degree of cross-linking, viscosity, consistency, stiffness, and injection force3
. November/December 2011 |
prime-journal.com over the last 10 years,
hyaluronic acid‑based products have established themselves as the gold standard for dermal fillers.
face using a soft tissue expander (the Princess range of hyaluronic acid fillers). At the end of the follow-up period of 240 days, the treatment reached the expectations of more than 70% of patients. Short-term reactions were transient and obviously related to the injection procedure (e.g. redness, swelling and pain). No long-term adverse reactions were reported, proving that the product was well tolerated.
Conclusions: The results confirm that the Princess Filler is an effective soft tissue filler with an excellent safety profile.
he InjecTIon of dermal fIllers for The creaTIon of a more youthful appearance is an increasingly popular procedure. over the last 10 years, hyaluronic acid‑based products have established themselves as the gold standard for dermal fillers1
. The main reasons
for the increasing popularity of hyaluronic acid fillers are their extremely low immunogenic potential, their biocompatibility and
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