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ARTICLE | research report | luminescent intensity. these readings provide Ra


Average line


Figure 3 Micro-relief values


Rp Rv


reference points that enable the system to be consistently calibrated from one use to the next. cutaneous micro-relief (Figure 3) measurements


Rt


Figure 4 Information provided by the IntuiSkin WorkStation


performed using the micro-relief module are based on definitions of metrology. the readings are expressed in gray levels (GL). this method provides the data required to transform a 2D picture of height and depth to a 3D image. the GL changes from one image to the next to represent the dynamic of biometric properties of the skin. the range of measurement is 0–255. Figure 3 refers to the following parameters: ■ average distance from tuberose ‘ra’ (GL) ■ Maximal depression depth ‘rv’ (GL) ■ Depth of peaks ‘rp’ (GL) ■ total height ‘rt’ (GL) ■ Density of peaks ‘pc’ (mm-1) ■ average space between irregularities ‘sM’ (µm). the 2D parameters are expressed in mm or µm. the


calculated surfaces are expressed in mm². In addition to information related to anisotropy, pigmentation, luminance, and other variables of tuberosity, both skin photography and a 3D reconstruction of the skin’s surface are provided.


Previous studies the current study is a confirmation of preliminary, unpublished work carried out by amgar and Bersand15


in


2009. It included 18 volunteer participants (six men and 12 women) aged between 30 and 75 years. this preliminary study demonstrated that the best results are obtained in the age group of 40–60 years, with a more effective response observed in women. For subjects younger than 40 years and older than 60 years, little or no improvement was observed, with an occasional occurrence of deterioration. the conclusions from the preliminary study were used to assist in the formulation of the inclusion/exclusion criteria for the present study. Inclusion criteria were as follows: ■ Female ■ aged 40–60 years ■ class 2 or 3 on the Glogau scale of photoageing (moderate or advanced wrinkles) ■ No previous prp treatments ■ signed informed consent. exclusion criteria were: ■ history of cancer ■ Use of anticoagulants or blood products ■ active facial skin infection ■ haematological diseases ■ pregnancy.


Schedule the protocol included three separate visits.


34 ❚


Visit 0 (V0) on Day 0 (D0) ■ administrative data collection (e.g. medical history, family history) ■ subjective skin evaluation ■ Biometric measurements


November/December 2011 | prime-journal.com


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